Results 81 to 90 of about 57,803 (200)

Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei   +5 more
wiley   +1 more source

Accelerated Biological Aging, Neurodegenerative Disease, and Mortality in Cardiovascular Disease Patients: Mediation and Modification Analysis

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
In cardiovascular disease (CVD) patients, accelerated biological aging is independently associated with elevated mortality risk, which is mediated by neurodegenerative disease. Early‐onset CVD amplifies the mortality risk, whereas a healthy lifestyle confers partial protection.
Jinyue Li, Han Ma, Guohua Wang
wiley   +1 more source

POSTPRANDIAL ANGINA PECTORIS

open access: yesТерапевтический архив, 2012
The article present literature and original data on rare cases of postprandial angina which is a symptom of postprandial syndrome. The latter is characterized with dyslipidemia, endothelial dysfunction, proinflammatory and prothrombogenic shifts in the ...
D M Aronov
doaj  

The role of leuko‐glycemic index in predicting 30‐day mortality in diabetic and non‐diabetic patients with acute coronary syndrome

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Background The leuko‐glycemic index (LGI) has been suggested as a possible prognostic marker for Acute coronary syndrome (ACS) but, its predictive capacity for mortality, especially among individuals with diabetes, remains poorly understood.
Ahmet Öztürk   +6 more
wiley   +1 more source

Ischemic Heart Disease in the Middle East and North Africa, 1990–2021: An Integrated Analysis of Temporal Trends, Country‐Level Variation, SDI Patterns, and Risk Factors

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Ischemic heart disease (IHD) remains a leading cause of mortality and disability worldwide. Using Global Burden of Disease (GBD) 2021 estimates, this study provides an integrated assessment of IHD burden across the Middle East and North Africa (MENA) region from 1990 to 2021, highlighting temporal trends, inter‐country heterogeneity,
Nahid Karamzad   +7 more
wiley   +1 more source

Apigenin, Selenium, and Combinations Are Effective in Preventing 5‐Fluorouracil Induced Cardiovascular Damage

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
5‐Fluorouracil (5‐FU) induces cardiovascular toxicity by increasing ROS, MDA, Bax, and caspase‐3 while decreasing antioxidant defenses and Bcl‐2 levels. Apigenin and selenium enhance antioxidant capacity, restore Bcl‐2 expression, suppress apoptosis, and rebalance redox status.
Gözde Atila Uslu   +4 more
wiley   +1 more source

PERCEPTION, ASSESSMENT AND RESPONSE TO THE SYMPTOM ANGINA PECTORIS BY WOMEN WHO PRESENTED ACUTE CORONARY SYNDROME (IN SPANISH)

open access: yesRevista Ciencias Biomédicas, 2014
Introduction: The coronary heart disease (CHD) is the cause number one of death in the occidental world and it is an important problem of public health with worldwide significance.
Almanza-Vega Nanchi Nahurlandy   +3 more
doaj  

Associations of Inherited Chromosomally‐Integrated Human Herpesvirus 6 With Dementia Incidence, Inflammation, and Other Dementia Risk Factors in the UK Biobank

open access: yesJournal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT The infection theory of dementia states that viral infections and chronic inflammation play a role in its pathogenesis. We aimed to test whether testing positive for inherited chromosomally‐integrated human herpesvirus 6 (iciHHV‐6) is associated with an increased dementia incidence, inflammation, and other dementia risk factors. We included n =
Zhong Qiya   +5 more
wiley   +1 more source

Quality of life in patients with angina pectoris

open access: yesPayesh, 2014
Objective (s): Angina pectoris greatly affects quality of life. The aim of this study was to examine quality of life and related factors in patients with angina pectoris.
Zahra Taheri Kharame   +4 more
doaj  

Coronary Microvascular Dysfunction: Epidemiology, Pathophysiology, Diagnosis, and Treatment

open access: yesMedComm, Volume 7, Issue 8, August 2026.
This visual summary illustrates the key aspects of coronary microvascular dysfunction (CMD) in angina with nonobstructive coronary artery disease (NOCAD), including epidemiology, pathophysiology (microvascular remodeling and endothelial dysfunction), the protective NRG‐1/ErbB signaling pathway, diagnostic methods, and both Western and traditional ...
Zhao Ge   +8 more
wiley   +1 more source

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