Results 81 to 90 of about 57,803 (200)
Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei +5 more
wiley +1 more source
In cardiovascular disease (CVD) patients, accelerated biological aging is independently associated with elevated mortality risk, which is mediated by neurodegenerative disease. Early‐onset CVD amplifies the mortality risk, whereas a healthy lifestyle confers partial protection.
Jinyue Li, Han Ma, Guohua Wang
wiley +1 more source
The article present literature and original data on rare cases of postprandial angina which is a symptom of postprandial syndrome. The latter is characterized with dyslipidemia, endothelial dysfunction, proinflammatory and prothrombogenic shifts in the ...
D M Aronov
doaj
Abstract Background The leuko‐glycemic index (LGI) has been suggested as a possible prognostic marker for Acute coronary syndrome (ACS) but, its predictive capacity for mortality, especially among individuals with diabetes, remains poorly understood.
Ahmet Öztürk +6 more
wiley +1 more source
ABSTRACT Background Ischemic heart disease (IHD) remains a leading cause of mortality and disability worldwide. Using Global Burden of Disease (GBD) 2021 estimates, this study provides an integrated assessment of IHD burden across the Middle East and North Africa (MENA) region from 1990 to 2021, highlighting temporal trends, inter‐country heterogeneity,
Nahid Karamzad +7 more
wiley +1 more source
5‐Fluorouracil (5‐FU) induces cardiovascular toxicity by increasing ROS, MDA, Bax, and caspase‐3 while decreasing antioxidant defenses and Bcl‐2 levels. Apigenin and selenium enhance antioxidant capacity, restore Bcl‐2 expression, suppress apoptosis, and rebalance redox status.
Gözde Atila Uslu +4 more
wiley +1 more source
Introduction: The coronary heart disease (CHD) is the cause number one of death in the occidental world and it is an important problem of public health with worldwide significance.
Almanza-Vega Nanchi Nahurlandy +3 more
doaj
ABSTRACT The infection theory of dementia states that viral infections and chronic inflammation play a role in its pathogenesis. We aimed to test whether testing positive for inherited chromosomally‐integrated human herpesvirus 6 (iciHHV‐6) is associated with an increased dementia incidence, inflammation, and other dementia risk factors. We included n =
Zhong Qiya +5 more
wiley +1 more source
Quality of life in patients with angina pectoris
Objective (s): Angina pectoris greatly affects quality of life. The aim of this study was to examine quality of life and related factors in patients with angina pectoris.
Zahra Taheri Kharame +4 more
doaj
Coronary Microvascular Dysfunction: Epidemiology, Pathophysiology, Diagnosis, and Treatment
This visual summary illustrates the key aspects of coronary microvascular dysfunction (CMD) in angina with nonobstructive coronary artery disease (NOCAD), including epidemiology, pathophysiology (microvascular remodeling and endothelial dysfunction), the protective NRG‐1/ErbB signaling pathway, diagnostic methods, and both Western and traditional ...
Zhao Ge +8 more
wiley +1 more source

