Results 141 to 150 of about 251,433 (257)

Correction to: Dynamics in zebrafish development define transcriptomic specificity after angiogenesis inhibitor exposure. [PDF]

Arch Toxicol
Nöth J, Michaelis P, Schüler L, Scholz S, Krüger J, Haake V, Busch W.   +6 more
europepmc   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Dynamics in zebrafish development define transcriptomic specificity after angiogenesis inhibitor exposure. [PDF]

Arch Toxicol
Nöth J, Michaelis P, Schüler L, Scholz S, Krüger J, Haake V, Busch W.   +6 more
europepmc   +1 more source

Brain-specific angiogenesis inhibitor 1 is expressed in the Myo/Nog cell lineage. [PDF]

PLoS One, 2020
Gerhart J, Bowers J, Gugerty L, Gerhart C, Martin M, Abdalla F, Bravo-Nuevo A, Sullivan JT, Rimkunas R, Albertus A, Casta L, Getts L, Getts R, George-Weinstein M.   +13 more
europepmc   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source

Neoadjuvant Chemotherapy With the Angiogenesis Inhibitor Bevacizumab for Locally Advanced Cervical Cancer. [PDF]

In Vivo
Baek S, Noh KW, Zhao Y, Schoemig-Markiefka B, Ratiu D, Domroese C, Mallmann M, Mallmann P, Pilch H.   +8 more
europepmc   +1 more source

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

RETRACTED: Kim et al. The Angiogenesis Inhibitor ALS-L1023 from Lemon-Balm Leaves Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease Through Regulating the Visceral Adipose-Tissue Function. <i>Int. J. Mol. Sci.</i> 2017, <i>18</i>, 846. [PDF]

Int J Mol Sci
Kim J, Lee H, Lim J, Oh J, Shin SS, Yoon M.   +5 more
europepmc   +1 more source

Editorial: Angiogenesis and Angiogenesis Inhibitors in Oral Cancer

Frontiers in Oral Health, 2021
Abdelhakim Salem, Abdelhakim Salem, Elin Hadler-Olsen, Elin Hadler-Olsen, Ahmed Al-Samadi, Ahmed Al-Samadi   +5 more
doaj   +1 more source

A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation

Advanced Science, EarlyView.
A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang, Simeng Chen, Qiaozhen Liu, Wenwen Ni, Xi Xu, Jianfa Zhang   +5 more
wiley   +1 more source