Results 291 to 300 of about 182,387 (331)
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Emoxypine as an inhibitor of angiogenesis
Bulletin of Experimental Biology and Medicine, 1992The effect of emoxypin on angiogenesis in rabbit cornea in aseptic inflammation induced by intracorneal implantation of a piece of quartz and on the development of the vessels of the chick embryo yolk sac was studied. 1% emoxypin pipetted thrice a day for 10-14 days inhibited corneal neovascularization and reduced the formation of new blood vessels. We
A. A. Sologub+2 more
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Metalloproteinases and their inhibitors in angiogenesis
Expert Reviews in Molecular Medicine, 2003Angiogenesis, the formation of new blood vessels from the pre-existing vasculature, is an integral part of physiological processes such as embryonic development, the female reproductive cycle and wound healing. Angiogenesis is also central to a variety of pathologies including cancer, where it is recognised as being crucial for the growth of solid ...
Lafleur, M.A.+2 more
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Heparin Derivatives as Angiogenesis Inhibitors
Current Pharmaceutical Design, 2003Angiogenesis is the process of generating new capillary blood vessels. Uncontrolled endothelial cell proliferation is observed in tumor neovascularization and in angioproliferative diseases. Tumors cannot growth as a mass above few mm(3) unless a new blood supply is induced. It derives that the control of the neovascularization process may affect tumor
PRESTA, Marco+8 more
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Thrombospondin as an Inhibitor of Angiogenesis [PDF]
Most normal, healthy adult tissues exist in a state of vascular quiescence that is sustained by a combination of influences that include embryonic factors (1), associated cells (2) and an overall balance of angiogenic factors in which inhibitors predominate over inducers (3).
Noel P. Bouck, David W. Dawson
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CURCUMIN AS AN INHIBITOR OF ANGIOGENESIS
2007Angiogenesis, the formation of new blood vessels from host vasculature, is critical for tumor growth and metastases. -Curcumin, a novel small-molecular-weight compound, has been shown to inhibit carcinogenesis in different organs and the common link between these actions is its antiangiogenic effect.
Sulochana S. Bhandarkar, Jack L. Arbiser
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Tumor angiogenesis inhibitors.
Biochemistry. Biokhimiia, 2003Formation of the blood supply system is a critical step in malignant transformation of neoplasms which results in the penetration of tumor cells into neighboring tissues and metastatic growth. Significant progress in the elucidation of mechanisms underlying tumor angiogenesis and the discovery of a great diversity of biomolecules involved in its ...
Severin Se+3 more
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A diaminoantraquinone inhibitor of angiogenesis.
The Journal of Pharmacology and Experimental Therapeutics, 1994Tumor growth is dependent upon angiogenesis. There is an intense search for pharmacological inhibitors of angiogenesis as a novel approach to treat angiogenic diseases, e.g., arthritis, diabetic retinopathy or cancer. A series of compounds, originally studied as potential protein kinase C inhibitors, included the diaminoanthraquinone NSC 639366 (1-[[3-(
S, Takano+3 more
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Cytokine and Angiogenesis Inhibitors
2005Renal cell carcinoma is an important malignancy accounting for approximately 3% of all adult cancers [1]. The incidence of renal cell carcinoma has been steadily and significantly increasing over the past two decades, with worldwide mortality expected to exceed 100,000 [2].
Timothy G. Eisen+2 more
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Angiogenesis inhibitors and their delivery systems
Applied Biochemistry and Biotechnology, 1983The extensive vascularity of solid tumors has been recognized for over 100 yr (1). However, only in the past 15 yr has the importance of this phenomenon been appreciated and only in the past 6 yr has the possibility of chemical interference been apparent. In this article, we review the emerging field of tumor vascularization inhibitors.
Robert Langer+3 more
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Angiogenesis inhibitors in human endometrium
2022This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
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