Results 61 to 70 of about 1,919 (181)

To laser or not?

Indian Journal of Ophthalmology, 2018
A 64-year-old male patient presented to the clinic with diminished vision in his right eye for the past 2 years. Examination revealed a best-corrected visual acuity (BCVA) of counting fingers at 1 m with a scarred choroidal neovascular membrane (CNVM) in
Vishal Govindhari, Jay Chhablani
doaj   +1 more source

Pseudoxanthoma elasticum: biopsy of clinically normal skin in the investigation of patients with angioid streaks

, 2007
Background Pseudoxanthoma elasticum (PXE) is a genetic disorder characterized by fragmentation and calcification of elastic fibres with resultant pathological changes in the dermis, Bruch's membrane and blood vessels.
Taylor, A. E. M., Brown, Sara, Talks, S. J., Needham, S. J.   +3 more
core   +1 more source

Microsomal triglyceride transfer protein is necessary to maintain lipid homeostasis and retinal function

The FASEB Journal, Volume 38, Issue 5, 15 March 2024.
The healthy RPE (left) plays a crucial role in maintaining photoreceptor health and function, in part, via the uptake (e.g., outer segment phagocytosis, plasma lipid absorption, and de novo lipid synthesis), processing (e.g., lipid oxidation and metabolism), and removal or recycling (e.g., β‐lipoproteins and HDL) of prodigious amounts of lipid. However,
Catharina R. Grubaugh, Anuradha Dhingra, Binu Prakash, Diego Montenegro, Janet R. Sparrow, Lauren L. Daniele, Christine A. Curcio, Brent A. Bell, M. Mahmood Hussain, Kathleen Boesze‐Battaglia   +9 more
wiley   +1 more source

Long-term follow-up of choroidal neovascularization secondary to angioid streaks: case series and literature review

Clinical Ophthalmology, 2012
Saba Al-Rashaed, J Fernando ArevaloKing Khaled Eye Specialist Hospital, Riyadh, Saudi ArabiaBackground: The purpose of this paper is to report the clinical course of choroidal neovascularization (CNV) secondary to angioid streaks and the outcomes in ...
Al-Rashaed S, Arevalo JF
doaj  

Novel Human Induced Pluripotent Stem Cell‐Based Model for Retinal Pigment Epithelial Cells to Reveal Possible Disease Mechanisms for Macular Degeneration in Pseudoxanthoma Elasticum

Journal of Ophthalmology, Volume 2024, Issue 1, 2024.
Pseudoxanthoma elasticum (PXE) is a rare metabolic disease with autosomal recessive inheritance. The manifestation in PXE is represented by retinal complications, pseudoxanthomas of the skin folding areas, and arterial calcification. The retinal complications are caused by the calcification of Bruch’s membrane beneath retinal pigment epithelial cells ...
Taina Viheriälä, Heidi Hongisto, Lyydia Saari, Marika Oksanen, Tanja Ilmarinen, Suvi Väärämäki, Hannu Uusitalo, Pasi Nevalainen, Heli Skottman, Nóra Szentmáry   +9 more
wiley   +1 more source

Angioid streaks: complications - treatment

, 2006
Angioid streaks are irregular crack like dehiscences in Bruch's membrane that invariably radiate outward from the peripapillary area in all directions9. They are associated with a wide variety of systemic diseases, such as pseudoxanthoma elasticum, Ehler-
Γεωργαλάς, Ηλίας, Georgalas, Ilias   +1 more
core   +1 more source

The extent of angioid streaks correlates with macular degeneration in pseudoxanthoma elasticum [PDF]

, 2020
Purpose: To investigate whether the extent of Bruch's membrane calcification is associated with choroidal neovascularization (CNV) and macular atrophy in patients with pseudoxanthoma elasticum (PXE) by using the extent of angioid streaks as a surrogate ...
van Leeuwen, Redmer, Risseeuw, Sara, Imhof, Saskia M, Ossewaarde-van Norel, Jeannette, van Buchem, Colette, Spiering, Wilko   +5 more
core  

Expanding the Interface: Overlooked Dermatologic Disorders With Ocular Involvement

JEADV Clinical Practice, Volume 4, Issue 5, Page 1239-1243, December 2025.
A George
wiley   +1 more source

A case of pseudoxanthoma elasticum with proliferative diabetic retinopathy

BMC Ophthalmology, 2017
Background To report the case of a patient with pseudoxanthoma elasticum (PXE) and proliferative diabetic retinopathy (PDR), and discuss the relationship between PXE and diabetic retinopathy (DR).
Keigo Kakurai, Maiko Hayashi, Kanako Yamada, Norihiko Ishizaki, Yumiko Yonemoto, Seita Morishita, Ryohsuke Kohmoto, Takaki Sato, Teruyo Kida, Tsunehiko Ikeda   +9 more
doaj   +1 more source

Calcinosis cutis of the lower legs – hyperphosphatemic familial tumoral calcinosis in a patient with GALNT3 mutation

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 9, Page 1144-1146, September 2025.
David Ranzinger, Tobias Schaefer, Franziska Schauer, Kilian Eyerich, Anna Caroline Pilz   +4 more
wiley   +1 more source