Results 41 to 50 of about 15,858 (169)

MCL‐1 inhibition triggers a largely reversible cardiac stress signature in a humanised mouse model

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Myeloid cell leukaemia‐1 (MCL‐1) is an essential anti‐apoptotic protein and a promising therapeutic target in oncology. Early clinical studies of MCL‐1 inhibitors reported unexpected elevations in cardiac troponin, raising concerns about potential cardiotoxicity.
Markus B. Heckmann, Zsanett Papdi, Nils J. Strauch, Daniel Finke, Marc‐Steffen Raab, Antje Blank, Norbert Frey, Lorenz H. Lehmann   +7 more
wiley   +1 more source

Prof. Armando Mansilha

Gazeta Médica, 2017
• Professor of Angiology and Vascular Surgery of the Faculty of Medicine of University of Porto • Head of the Department of Angiology and Vascular Surgery at Hospital CUF Porto • Secretary General of the Section and Board of Vascular Surgery of the ...
Armando Mansilha, MD, PhD, FEBVS
doaj   +2 more sources

Outpatient care for venous leg ulceration in Germany: A retrospective claims data analysis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Outpatient care of venous leg ulcers (VLU) is a problem of high medical and health economic relevance. Treatment is often inconsistent and not guideline‐compliant. The project Ulcus Cruris Care investigated the VLU outpatient care situation in Germany.
Lisa Weller, Regina Poß‐Doering, Thomas Grobe, Thomas Fleischhauer, Gunter Laux, Jona Frasch, Attila Altiner, Kerstin Protz, Joachim Szecsenyi, Jonas D. Senft   +9 more
wiley   +1 more source

Vascular alterations among male elite athletes recovering from SARS-CoV-2 infection

Scientific Reports, 2022
SARS-CoV-2 may affect the cardiovascular system and vascular impairment has been reported in healthy young adults recovering from COVID-19. However, the impact of SARS-CoV-2 infection on the vascular function of elite athletes is unknown.
Pascal Bauer, Lutz Kraushaar, Oliver Dörr, Stanislav Keranov, Holger Nef, Christian W. Hamm, Astrid Most   +6 more
doaj   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Attenuating Effects of Anti-Arrhythmic Agents on Changes in Fibrillation Cycle Length in Very Early Phase Paroxysmal Atrial Fibrillation —Spectral Analysis of Fibrillation Waves in Surface ECG—

Journal of Arrhythmia, 2009
Background: Antiarrhythmic agents may affect electrical remodeling but little is known regarding clinical cases. We evaluated fibrillation cycle length (FCL) of atrial fibrillation (AF) by spectral analysis of fibrillation waves (FW) in surface ECG for ...
Hidehira Fukaya, MD, Shinichi Niwano, MD, Takeshi Sasaki, MD, Michiro Kiryu, MD, Sayaka Kurokawa, MD, Yuko Hatakeyama, MD, Daisuke Sato, MD, Yoshihiro Yumoto, MD, Masahiko Moriguchi, MD, Hiroe Niwano, MD, Akira Fujiki, MD, Tohru Izumi, MD   +11 more
doaj   +1 more source

Determinant Factors of Self‐Care Deficit in People With Chronic Wounds: A Scoping Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To identify and synthesise the scientific evidence on determinants of self‐care deficits in people with chronic wounds. Design Scoping review based on the Joanna Briggs Institute guidelines. Methods This scoping review was conducted by a review team responsible for study screening, data extraction and synthesis.
Janislei Soares Dantas, Yan Lincoln Mamede Gomes, Ana Clara de Macedo Farias Ramos, Selene Cordeiro Vasconcelos, Maria Eliane Moreira Freire   +4 more
wiley   +1 more source

Modelo de suprimento sanguíneo do intestino delgado e grosso da preguiça de coleira (Bradypus torquatus) Blood supply model of the small and large intestine of the maned three-toed sloth (Bradypus torquatus)

Ciência Rural, 2013
O Bradypus torquatus, conhecido como preguiça de coleira, está classificado na lista vermelha da IUCN como vulnerável. Este animal é um folívoro estrito que se alimenta de um pequeno número de plantas. O suprimento sanguíneo do intestino delgado e grosso
Jussara Rocha Ferreira, Lorenna Cardoso Rezende, Phellip Carvalho, Amanda Rocha Mortoza, Daniele dos Santos Martins   +4 more
doaj  

Pharmacotherapy of chronic vein diseases. New European guidelines

Амбулаторная хирургия, 2018
The 19th Annual Meeting of the European Venous Forum held in the city of Athens in 28-30 June 2018 presented the long-awaited updated guidelines for the diagnosis and treatment of chronic venous diseases (CVD), the full text of which can be found in the ...
V. Yu. Bogachev, S. V. Rodionov, O. V. Dzhenina   +2 more
doaj   +1 more source

QT Interval Evaluation in Right Ventricular Pacing: Validation of a Novel Formula

Pacing and Clinical Electrophysiology, EarlyView.
Abstract Background QT interval measurement in the presence of right ventricular pacing (RVP) represents a clinical challenge. We therefore aimed to derive and validate a formula for QT estimation during RVP in a large cohort of pacemaker patients. Methods and Results We prospectively enrolled 100 patients in a derivation cohort and 487 in a validation
Amr Abdin, Alhasan Almasri, Ibrahim Antoun, Charles Gieres, Christian Werner, Yvonne Bewarder, Christian Ukena, Igor Schwantke, Michael Böhm, Saarraaken Kulenthiran   +9 more
wiley   +1 more source