Results 101 to 110 of about 55,141 (338)
Cerebral Amyloid Angiopathy and Blood-Brain Barrier Dysfunction
The Neuroscientist, 2020 Cerebral hemorrhage, a devastating subtype of stroke, is often caused by hypertension and cerebral amyloid angiopathy (CAA). Pathological evidence of CAA is detected in approximately half of all individuals over the age of 70 and is associated with ...
Monica Gireud-Goss +3 more
semanticscholar +1 more source
Dissecting the Crosstalk between Endothelial Mitochondrial Damage, Vascular Inflammation, and Neurodegeneration in Cerebral Amyloid Angiopathy and Alzheimer’s Disease [PDF]
, 2021 Rebecca Parodi‐Rullán +2 more
openalex +1 more source
PROTEOMICS, EarlyView.ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and pathological protein aggregation. Comprehensive quantitative proteomics of brain tissues from AD patients is critical for pursuing a better understanding of the molecular mechanisms that drive AD progression.
Mehrdad Falamarzi Askarani +3 more
wiley +1 more source
Scientific Reports, 2020 Alzheimer’s disease patients typically present with multiple co-morbid neuropathologies at autopsy, but the impact of these pathologies on cognitive impairment during life is poorly understood.
David X. Thomas +5 more
semanticscholar +1 more source
Vascular neurocognitive disorders and the vascular risk factors [PDF]
, 2018 Dementias are clinical neurodegenerative diseases characterized by permanent and progressive transformation of cognitive functions such as memory, learning capacity, attention, thinking, language, passing judgments, calculation or orientation.
Albu, Carmen V. +7 more
core +4 more sources
Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix
PROTEOMICS, EarlyView.ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov +3 more
wiley +1 more source
Ultrastructure in Transthyretin Amyloidosis: From Pathophysiology to Therapeutic Insights
Biomedicines, 2019 Transthyretin (TTR) amyloidosis is caused by systemic deposition of wild-type or variant amyloidogenic TTR (ATTRwt and ATTRv, respectively). ATTRwt amyloidosis has traditionally been termed senile systemic amyloidosis, while ATTRv amyloidosis has been ...
Haruki Koike, Masahisa Katsuno
doaj +1 more source
The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice
Journal of Neurology Neurosurgery & Psychiatry, 2017 Cerebral amyloid angiopathy (CAA) has never been more relevant. The last 5 years have seen a rapid increase in publications and research in the field, with the development of new biomarkers for the disease, thanks to advances in MRI, amyloid positron ...
G. Banerjee +9 more
semanticscholar +1 more source
Noninvasive imaging of amyloid‐beta and tau in rodent and nonhuman primate models
VIEW, EarlyView.Imaging of amyloid‐beta plaque and tau accumulation in rodent and nonhuman primate model of Alzheimer's disease. Created in BioRender. Ni R. 2026. https://BioRender.com/a97h5ec Abstract Neurodegenerative diseases are characterized by the aberrant accumulation of protein aggregates.
Ruiqing Ni, Axel Rominger
wiley +1 more source
Наука. Инновации. Технологии, 2022 The problem of diabetes and its complications is currently very important. The study of this question, as a mechanism for the development of vascular complications in patients with diabetes is increasingly becoming the subject of scientific research. For
Tatiana Petrovna Bondar +1 more
doaj