Results 111 to 120 of about 42,626 (296)

Comorbidity of cerebral amyloid angiopathy and Alzheimer's disease. Clinical case analysis

, 2023
A. Yu. Emelin, V. Yu. Lobzin, A. Yu. Efimtsev, S. V. Vorobyov   +3 more
openalex   +1 more source

The photoplethysmography potential for the early diagnosis of diabetic angiopathy of the lower limbs

Mìžnarodnij Endokrinologìčnij Žurnal, 2017
Background. In most cases of diabetes mellitus (DM), a complication in the form of diabetic angiopathy of the lower limbs is diagnosed rather late when clinical manifestations of vascular pathology appear. Wellness activities at this stage are palliative,
L.V. Vorobjov
doaj   +1 more source

ABCG2 Is Upregulated in Alzheimer's Brain with Cerebral Amyloid Angiopathy and May Act as a Gatekeeper at the Blood–Brain Barrier for Aβ_1–40Peptides [PDF]

, 2009
Huaqi Xiong, Debbie Callaghan, Aimee Jones, Jianying Bai, Ingrid Rasquinha, Catherine Delano Smith, Ke Pei, Douglas G. Walker, Lih‐Fen Lue, Danica Stanimirovic, Wandong Zhang   +10 more
openalex   +1 more source

APOE isoform‐associated tau oligomer polymorphs differ in synaptotoxicity and seeding activity

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Pathological tau aggregates form distinct polymorphic species across diseases and even across Alzheimer's disease (AD) patients. However, tau aggregate polymorphism across the apolipoprotein E isoforms (APOE ε2, ε3, ε4), the strongest predictors of late‐onset AD development, is unknown.
Naomi Moreno, Nikita Shchankin, Leiana Fung, Nicha Puangmalai, Nemil Bhatt, Md Anzarul Haque, Yingxin Zhao, C. Dirk Keene, Agenor Limon, Rakez Kayed   +9 more
wiley   +1 more source

White matter hyperintensity modulates the amyloid‐tau‐cognition association and anti‐amyloid treatment efficacy in asymptomatic older adults

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION White matter hyperintensities (WMH), a key imaging biomarker of small vessel injury, may play a complex role in Alzheimer's disease (AD). We hypothesize that WMH not only directly contributes to cognitive decline but also moderates the relationship among AD pathology, treatment, and cognitive decline.
Zixuan Lin, Yiwen Hong, Yizhe Hu, Qian Xiao, Shin‐Lei Peng, Dan Wu, Tengfei Guo, Dengrong Jiang   +7 more
wiley   +1 more source

Monitoring the Patient with Retinal Angiopathy Associated with Hereditary Transthyretin Amyloidosis: Current Perspectives

Clinical Ophthalmology, 2022
João Heitor Marques,1 João Coelho,1 Maria João Menéres,1,2 João Melo Beirão1,2 1Serviço de Oftalmologia, Centro Hospitalar Universitário do Porto, Porto, Portugal; 2Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto ...
Marques JH, Coelho J, Menéres MJ, Melo Beirão J   +3 more
doaj  

Apolipoprotein E ε4 homozygosity exacerbates retinal and cerebral microvascular dysfunction in Alzheimer's disease: A mediation analysis of vascular contributions to cognitive decline

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Apolipoprotein E (APOE) ε4 is the strongest genetic risk factor for Alzheimer's disease (AD), with homozygous carriers (ε4/ε4) experiencing accelerated cognitive decline. While its role in amyloid and tau pathology is established, its impact on retinal and cerebral microvasculature remains underexplored. METHODS A total of 107 AD (
Yuntao Liu, Hanyu Zhu, Youjie Wang, Xiaoqian Luan, Jiahui Chen, Jiajing Qian, Jianing Shen, Yinhe Liu, Caiyun Wen, Lin Cao, Bo Tang, Ho Ko, William Robert Kwapong, Zhen Wang   +13 more
wiley   +1 more source

Relationship between cerebral amyloid angiopathy and plasma homocysteine levels in Alzheimer’s disease [PDF]

, 2020
Kazutomi Kanemaru, Akiko Kanemaru, Shigeo Murayama   +2 more
openalex   +1 more source

Systemic Piezo1 activation improves cerebrovascular function in Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Cerebral blood flow (CBF) reductions and impaired functional hyperemia (FH) are early features of Alzheimer's disease (AD) that contribute to disease progression. Here, we investigated whether systemic activation of the mechanosensitive ion channel Piezo1 affects cerebrovascular deficits in an AD mouse model.
Zeynab Tabrizi, Xin Rui Lim, Supriya Chakraborty, Osama F. Harraz, Oliver Bracko   +4 more
wiley   +1 more source

Inflammatory cerebral amyloid angiopathy with poor outcome – case report

, 2023
Dariusz Dziubek, Karolina Dziubek
openalex   +2 more sources