Results 151 to 160 of about 55,141 (338)

SGLT2 inhibitor or metformin as standard treatment in early‐stage type 2 diabetes? Baseline data in SMARTEST, a novel, decentralised, register‐based randomised trial on prevention of diabetic complications

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1327-1338, February 2026.
Abstract Aims Metformin has hitherto not been proven superior to other type 2 diabetes (T2D) medications for the prevention of organ complications. The aim of this study is to report baseline data and blinded interim analyses in the register‐based randomised clinical trial (RRCT) SMARTEST, which compares metformin and the SGLT2 inhibitor dapagliflozin ...
Jan W. Eriksson   +14 more
wiley   +1 more source

Pleiotropic neuroprotective effects of taxifolin in cerebral amyloid angiopathy

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Cerebrovascular amyloid-β deposition is highly implicated in the pathogenesis of cerebral amyloid angiopathy (CAA), one of the major causes of dementia.
Takayuki Inoue   +7 more
semanticscholar   +1 more source

Association of candidate genetic variants and circulating levels of ApoE/ApoJ with common neuroimaging features of cerebral amyloid angiopathy [PDF]

open access: gold, 2023
Anna Bonaterra‐Pastra   +19 more
openalex   +1 more source

Aquaporin‐4 and caveolin‐1 as mediators of fibrinogen‐driven cerebrovascular pathology in cerebral amyloid angiopathy

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Cerebral amyloid angiopathy (CAA), marked by amyloid beta (Aβ) accumulation in perivascular spaces (PVSs), contributes to vascular injury and inflammation in Alzheimer's disease. The mechanisms underlying CAA‐related vascular pathology remain unclear.
Vishal Singh   +7 more
wiley   +1 more source

Gray matter microstructure from in vivo diffusion magnetic resonance imaging reflects post mortem neuropathology severity and clinical progression of Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Diffusion‐weighted imaging derived mean diffusivity (MD) correlates with Alzheimer's disease (AD) biomarkers, yet its neuropathological correlates remain unclear. METHODS Diffusion‐weighted imaging, post mortem neuropathology, and cognitive performance data were obtained from the National Alzheimer's Coordinating Center (N = 97 ...
Zaki Alasmar   +9 more
wiley   +1 more source

The photoplethysmography potential for the early diagnosis of diabetic angiopathy of the lower limbs

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2017
Background. In most cases of diabetes mellitus (DM), a complication in the form of diabetic angiopathy of the lower limbs is diagnosed rather late when clinical manifestations of vascular pathology appear. Wellness activities at this stage are palliative,
L.V. Vorobjov
doaj   +1 more source

Mystery Case: Cerebral amyloid angiopathy–related inflammation [PDF]

open access: bronze, 2014
Aaron L. Berkowitz   +3 more
openalex   +1 more source

Six‐month follow‐up of ARIA‐H and iron deposition in real‐world lecanemab therapy for Alzheimer's disease: Evidence from a Chinese 7T MRI cohort

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION With the approval of lecanemab for treating Alzheimer's disease (AD), there is an urgent need to evaluate its safety and treatment effects on biomarkers in real‐world practice. METHODS Patients receiving lecanemab (n = 72) underwent routine 3T and 7T magnetic resonance imaging (MRI) for amyloid‐related imaging abnormality (ARIA ...
Weiwei Zhang   +12 more
wiley   +1 more source

Monitoring the Patient with Retinal Angiopathy Associated with Hereditary Transthyretin Amyloidosis: Current Perspectives

open access: yesClinical Ophthalmology, 2022
João Heitor Marques,1 João Coelho,1 Maria João Menéres,1,2 João Melo Beirão1,2 1Serviço de Oftalmologia, Centro Hospitalar Universitário do Porto, Porto, Portugal; 2Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto ...
Marques JH   +3 more
doaj  

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