Results 161 to 170 of about 55,141 (338)

Identifying early changes in imaging, plasma, and digital cognitive biomarkers that correspond to Alzheimer's disease pathology in the presence of autopsy‐confirmed co‐pathologies

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) biomarkers are assessed on their ability to detect AD pathophysiology in vivo, with confirmation of AD neuropathology only at autopsy. METHODS Positron emission tomography (PET), plasma, and cognitive AD biomarkers were compared to AD neuropathology in Harvard Aging Brain Study participants (10 cognitively
Charles D. Chen, Cinthya Aguero, Alexandra Melloni, Brian C. Healy, Emma G. Thibault, Jessie Fanglu Fu, Michelle E. Farrell, Stephanie Schultz, Hyun‐Sik Yang, Jean‐Pierre Bellier, Jasmeer Chhatwal, Pia Kivisäkk Webb, Steven Arnold, Dana Penney, Randall Davis, Dorene Rentz, Teresa Gomez‐Isla, Reisa A. Sperling, Keith A. Johnson, Julie C. Price   +19 more
wiley   +1 more source

The comparison of hearing loss among diabetic and non-diabetic patients [PDF]

, 2011
Introduction: The prevalence of Diabetes Mellitus is steadily increasing. This is a multi- systemic abnormality, causing side- effects which are mainly irreversible.
Mansourian Azad, R., Taziki Mohammad, H.
core  

Mechanisms of Dural Involvement in Cerebral Amyloid Angiopathy

Cells
Cerebral Amyloid Angiopathy (CAA) is a neurovascular condition characterized by the accumulation of amyloid-beta (Aβ) in the walls of small blood vessels, particularly affecting the leptomeninges and cortical regions in elderly populations.
Marialuisa Zedde, Fabrizio Piazza, Rosario Pascarella   +2 more
doaj   +1 more source

Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline.

Brain : a journal of neurology, 2022
J. Rabin, E. Nichols, R. La Joie, K. Casaletto, P. Palta, K. Dams-O’Connor, Raj G. Kumar, K. George, C. Satizabal, J. Schneider, J. Pa, A. Brickman   +11 more
semanticscholar   +1 more source

COVID-19 Presenting With Thalamic Hemorrhage Unmasking Moyamoya Angiopathy [PDF]

, 2020
Ritwik Ghosh, Souvik Dubey, Biman Kanti Ray, Subhankar Chatterjee, Julián Benito‐León   +4 more
openalex   +1 more source

Aβ antibodies target not only amyloid plaques but also distinct brain cells and vessels

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract BACKGROUND Amyloid beta (Aβ) antibodies are the only therapies to slow cognitive decline in Alzheimer's disease (AD). Yet the sites where antibodies engage Aβ in the brain and mechanisms that lower Aβ are not fully understood. Defining Aβ antibody localizations in the brain is essential to understand how immunotherapy is beneficial for AD ...
Gehua Wen, Nils Lindblom, Xiaoni Zhan, Megg Garcia‐Ryde, Tomas Deierborg, Asgeir Kobro‐Flatmoen, Gunnar K. Gouras   +6 more
wiley   +1 more source

Moyamoya disease emerging as an immune-related angiopathy.

Trends in Molecular Medicine, 2022
Caroline Asselman, D. Hemelsoet, Denzel Eggermont, B. Dermaut, Francis Impens   +4 more
semanticscholar   +1 more source

Plasma extracellular vesicles from APOE3 Christchurch carriers display a protective phenotype in early stages of autosomal dominant Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The PSEN1E280A mutation causes autosomal dominant Alzheimer's disease (ADAD) with predictable onset, enabling presymptomatic studies. Extracellular vesicles (EVs) are emerging biomarkers of cognitive decline, but their role in early ADAD is unclear.
Lina Pineda‐Lopez, David Aguillon, Juan Villar‐Vesga, Pablo Valderrama‐Carmona, Alejandro Guerrero, Anil Upreti, Said Arevalo‐Alquichire, Laura Correa, Karin Mendez‐Castellanos, Diana Castaño, Gloria P. Cardona‐Gomez, Geysson J. Fernandez, Leo A. Kim, Joseph F. Arboleda‐Velasquez, Rafael Posada‐Duque   +14 more
wiley   +1 more source

Mesenchymal stem cells overexpressing XIST induce macrophage M2 polarization and improve neural stem cell homeostatic microenvironment, alleviating spinal cord injury

Journal of Tissue Engineering
Spinal cord injury (SCI) is a significant cause of disability worldwide, with limited treatment options. This study investigated the potential of bone marrow-derived mesenchymal stem cells (BMSCs) modified with XIST lentiviral vector to modulate ...
Dan Zhu, Tie Peng, Zhenwang Zhang, Shuang Guo, Ying Su, Kangwei Zhang, Jiawei Wang, Chao Liu   +7 more
doaj   +1 more source

Superficial siderosis: a potential diagnostic marker of cerebral amyloid angiopathy in Alzheimer disease [PDF]

, 2008
BACKGROUND AND PURPOSE: Superficial siderosis of the central nervous system results from chronic bleeding in the superficial layers of the cortex and spinal cord.
Feldman, H., Forster, B., Mackenzie, I., Maia, L., Martzke, J., Woolfenden, A.   +5 more
core