Results 31 to 40 of about 168,406 (311)

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Two‐Stage Treatment for Adult Large Patent Ductus Venosus

Annals of Gastroenterological Surgery, EarlyView.
This is the first report of a two‐stage treatment for an adult large PDV involving the first stage surgical angioplasty of the large Arantius' duct and second stage embolization of the formed small Arantius' duct. The two‐stage approach could avoid embolic material migration into the systemic circulation or acute portal hypertension associated with the
Shohei Kudo, Shiro Onozawa, Ryosuke Miyauchi, Ryota Matsuki, Yoshihiro Sakamoto   +4 more
wiley   +1 more source

Magnetic Particle / Magnetic Resonance Imaging: In-Vitro MPI-Guided Real Time Catheter Tracking and 4D Angioplasty Using a Road Map and Blood Pool Tracer Approach

PLoS ONE, 2016
Purpose In-vitro evaluation of the feasibility of 4D real time tracking of endovascular devices and stenosis treatment with a magnetic particle imaging (MPI) / magnetic resonance imaging (MRI) road map approach and an MPI-guided approach using a blood ...
J. Salamon, M. Hofmann, C. Jung, M. Kaul, F. Werner, K. Them, R. Reimer, P. Nielsen, A. vom Scheidt, G. Adam, T. Knopp, H. Ittrich   +11 more
semanticscholar   +1 more source

Influence of the arterial elastic component on the response to balloon angioplasty in femoral arteries of a healthy porcine model

Animal Models and Experimental Medicine, EarlyView.
This study evaluates the role of elastin in vascular response 28 days after balloon angioplasty using uncoated and paclitaxel‐coated balloons in a healthy porcine model. The results show higher elastin content in external femoral arteries, which is inversely correlated with vascular injury, inflammation, smooth muscle cell loss, proteoglycan and fibrin
María Gracia de Garnica García, Marina Gil Bernabé, Claudia Pérez‐Martínez, Laura Mola Solà, Luis Duocastella Codina, María Molina Crisol, Alex Gómez Castel, Armando Pérez de Prado   +7 more
wiley   +1 more source

Wound-directed revascularisation in the Diabetic Foot patients

Journal of Education, Health and Sport, 2016
Introduction: Peripheral arterial diseases in patients with diabetic foot have significant features in pathogenesis, manifestations and course compared with peripheral arterial disease.
N. Kononenko, A. Sheikhali
doaj   +1 more source

Efficacy of Direct Injection in Occlusive Lesion (DIOL) Fashion for Infrapopliteal and Inframalleolar Chronic Total Occlusions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Endovascular therapy (EVT) for chronic total occlusions (CTOs) in patients with critical limb‐threatening ischemia (CLTI) remains technically challenging, particularly in infrapopliteal lesions. Direct injection in occlusive lesions (DIOL) fashion is a novel adjunctive strategy that utilizes hydraulic contrast injection through a ...
Takuya Haraguchi, Tsutomu Fujita, Masanaga Tsujimoto, Yuhei Kasai, Yoshifumi Kashima, Katsuhiko Sato   +5 more
wiley   +1 more source

Management of Lost Atherectomy Devices in the Coronary Arteries

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Rotational and orbital atherectomy are important tools to treat calcific coronary disease. Entrapment of an atherectomy device, that is, rotational atherectomy burr or orbital atherectomy crown, is a serious complication during atherectomy. Loss of an atherectomy device is a more challenging complication that usually follows device entrapment.
Gregor Leibundgut, Alexandru Achim, Daniel Weilenmann, Johannes Rigger, Fabian Gocht, Mohaned Egred, Bilal Murad, William Lombardi, M. Bilal Iqbal   +8 more
wiley   +1 more source

Drug Coated Balloons Versus Drug‐Eluting Stents in Patients With De Novo Coronary Artery Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background In patients with de novo coronary artery disease (CAD), percutaneous coronary intervention (PCI) with drug eluting stent (DES) implantation is the gold standard therapy. New evidence is available with drug coated balloons (DCB) angioplasty. The objective of this meta‐analysis was to compare the efficacy and safety of DCB angioplasty
Daniel O'Callaghan, Himanshu Rai, Daniele Giacoppo, J. J. Coughlan, Rory Durand, Valeria Paradies, Róisín Colleran, Gavin J. Blake, Fernando Alfonso, Robert A. Byrne   +9 more
wiley   +1 more source

Breaking the Barrier: Unraveling the No‐Reflow Phenomenon in Cardiovascular Medicine

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The no‐reflow phenomenon is a stubborn and often devastating complication in cardiovascular medicine, where blood flow is restored to an artery, yet the microvasculature remains unresponsive. First identified in 1967, this phenomenon has haunted clinicians and researchers alike, particularly in the context of acute myocardial infarction (AMI).
Stephanie Howes, Osamah Altaee, Ariana Ramirez, Loreto Calaquian, Anum Asif, Collin Stone, Muhammad Hammadah, Debanshu Roy, Bryan Ramsey, Robert Chilton   +9 more
wiley   +1 more source

Percutaneous transluminal angioplasty for isolated infrapopliteal arterial occlusive disease in diabetic patients with critical limb ischemia

Journal of Medicine in Scientific Research, 2020
Background Critical limb ischemia (CLI) is considered the most severe stage of peripheral artery disease. Patients with CLI typically have the disease affecting multiple levels (i.e. aortoiliac, femoropopliteal, and infrapopliteal).
Mohamad T Yousuf, Mohamad M Gouda, Asim M Herz-Allah, Sherine I Elwan   +3 more
doaj   +1 more source