Results 111 to 120 of about 28,342 (160)

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, Volume 10, Issue 3, Page 269-280, June 2026.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

Distinct Roles of Myeloid‐ and Hepatocyte‐PLA2G6 Deletion in Mice With Metabolic Dysfunction‐Associated Steatotic Liver Disease

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Polymorphisms of group VIA calcium‐independent phospholipase A2 (iPLA2β or PLA2G6) are associated with Type‐2 diabetes, blood lipids and inflammation. Global deficiency in iPLA2β‐null mice elicited protection against hepatic steatosis but not hepatic inflammation after high‐fat diet (HFD) feeding.
Gang Li, Simone Staffer, Sabine Tuma‐Kellner, Uta Merle, Walee Chamulitrat   +4 more
wiley   +1 more source

Integrative Analysis of Colonic Biopsies from Inflammatory Bowel Disease Patients Identifies an Interaction Between Microbial Bile Acid-inducible Gene Abundance and Human Angiopoietin-like 4 Gene Expression. [PDF]

J Crohns Colitis, 2021
Hernández-Rocha C, Borowski K, Turpin W, Filice M, Nayeri S, Raygoza Garay JA, Stempak JM, Silverberg MS.   +7 more
europepmc   +1 more source

From Theory to Practice: Which Biomarkers Are Ready for Predicting Response in Advanced HCC?

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Systemic therapies for advanced hepatocellular carcinoma (HCC) have expanded considerably with the advent of tyrosine kinase inhibitors, immune checkpoint inhibitors and immunotherapy–anti‐angiogenic combinations. However, despite this therapeutic diversification, first‐line treatment selection remains largely empirical, as few biomarkers are ...
Marie Decraecker, Jean‐Frédéric Blanc, Samuel Amintas, Grégoire Manaud   +3 more
wiley   +1 more source

A comparison of plasma Tsukushi in adolescents with and without metabolic dysfunction‐associated steatotic liver disease

Physiological Reports, Volume 14, Issue 12, June 2026.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common liver disease in children and adolescents. Assessment of circulating biomarkers is needed to understand the underlying pathology, disease severity, and treatment options.
Sydni A. McNeese, Sadie A. Maltz, Youngsil Kim, April M. Teague, Sirish K. Palle, Jacob E. Friedman, Kevin R. Short   +6 more
wiley   +1 more source

Inhibitory role of angiopoietin‑like 4 for cancer progression in oropharyngeal squamous cell carcinoma. [PDF]

Oncol Rep
Mikoshiba T, Sekimizu M, Nakahara N, Saito S, Yoshihama K, Nagai R, Kono T, Ozawa H.   +7 more
europepmc   +1 more source

Emerging roles of angiopoietin‑like 4 in human tumors (Review). [PDF]

Int J Oncol
Liu R, Fu M, Chen P, Liu Y, Huang W, Sun X, Zhu P, Wen Z, Cheng Y.   +8 more
europepmc   +1 more source

Expression of angiopoietin-like 4 fibrinogen-like domain (cANGPTL4) increases risk of brain metastases in women with breast cancer. [PDF]

Oncotarget, 2020
Dao T, Gapihan G, Leboeuf C, Hamdan D, Feugeas JP, Boudabous H, Zelek L, Miquel C, Tran T, Monnot C, Germain S, Janin A, Bousquet G.   +12 more
europepmc   +1 more source

Epidermal growth factor-induced COX-2 regulates metastasis of head and neck squamous cell carcinoma through upregulation of angiopoietin-like 4. [PDF]

Cancer Sci, 2020
Chiang KH, Shieh JM, Shen CJ, Chang TW, Wu PT, Hsu JY, Tsai JP, Chang WC, Chen BK.   +8 more
europepmc   +1 more source