Results 41 to 50 of about 1,202 (161)

Piplartine as an Innovative Natural Product With Dual Antiparasitic and Immunomodulatory Actions

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Neglected tropical diseases (NTDs) remain a major global health burden, disproportionately affecting low‐ and middle‐income regions and demanding innovative therapeutic strategies. This review summarizes current evidence on piplartine (piperlongumine), a naturally occurring amide from Piper species with broad antiparasitic and immunomodulatory ...
Lucas Fukui-Silva, Felipe C. R. de Souza, Camila S. Amorim, Josué de Moraes, Poorani Gurumallesh Prabu   +4 more
wiley   +1 more source

Activation of Sonic Hedgehog Leads to Survival Enhancement of Astrocytes via the GRP78‐Dependent Pathway in Mice Infected with Angiostrongylus cantonensis

BioMed Research International, Volume 2015, Issue 1, 2015., 2015
Angiostrongylus cantonensis infection may cause elevation of ROS and antioxidants in the CSF of infected mice. Astrocytes may protect the surrounding neurons from oxidative stress‐induced cell death by secreting Sonic hedgehog (Shh) via the PI3‐K/AKT/Bcl‐2 pathway.
Kuang-Yao Chen, Chien-Ju Cheng, Lian-Chen Wang, Ruijin Huang   +3 more
wiley   +1 more source

Distribution of Eosinophilic Meningitis Cases Attributable to Angiostrongylus cantonensis, Hawaii

Emerging Infectious Diseases, 2007
During November 2004–January 2005, 5 cases of eosinophilic meningitis (EM) attributable to Angiostrongylus cantonensis infection were reported in Hawaii.
Natasha S. Hochberg, Sarah Y. Park, Brian G. Blackburn, James J. Sejvar, Kate Gaynor, Heath Chung, Karyn Leniek, Barbara L. Herwaldt, Paul V. Effler   +8 more
doaj   +1 more source

Human angiostrongyliasis outbreak in Dali, China. [PDF]

PLoS Neglected Tropical Diseases, 2009
BackgroundSeveral angiostrongyliasis outbreaks have been reported in recent years but the disease continues to be neglected in public health circles. We describe an outbreak in Dali, southwest China in order to highlight some key problems for the control
Shan Lv, Yi Zhang, Shao-Rong Chen, Li-Bo Wang, Wen Fang, Feng Chen, Jin-Yong Jiang, Yuan-Lin Li, Zun-Wei Du, Xiao-Nong Zhou   +9 more
doaj   +1 more source

Hyperkalaemia secondary to suspected transient hyporeninaemic hypoaldosteronism in a dog (in a dog)

Veterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract A 12‐year‐7‐month‐old, female, entire beagle dog was presented to a referral hospital in England for a 10‐day history of tachypnoea and lethargy. Angiostrongylus vasorum ELISA test was positive, and the patient was started on fenbendazole. One week later, it became lethargic, anorexic, polyuric and polydipsic, and it was diagnosed with an open
Maria Jose Marin Lucas, Francesca Venier
wiley   +1 more source

Interface Molecules of Angiostrongylus cantonensis: Their Role in Parasite Survival and Modulation of Host Defenses

International Journal of Inflammation, Volume 2012, Issue 1, 2012., 2012
Angiostrongylus cantonensis is a nematode parasite that causes eosinophilic meningoencephalitis in humans. Disease presents following the ingestion of third‐stage larvae residing in the intermediate mollusk host and disease manifests as an acute inflammation of the meninges characterized by eosinophil infiltrates which release a battery of ...
Alessandra L. Morassutti, Carlos Graeff-Teixeira, Kittisak Sawanyawisuth   +2 more
wiley   +1 more source

Peripheral eosinophilia as an indicator of meningitic angiostrongyliasis in exposed individuals

Memorias do Instituto Oswaldo Cruz, 2010
The diagnosis of meningitic angiostrongyliasis (MA) is based on clinical criteria. A lumbar puncture is used as a diagnostic tool, but it is an invasive procedure.
Kittisak Sawanyawisuth, Kanlayanee Sawanyawisuth, Vichai Senthong, Panita Limpawattana, Pewpan M Intapan, Somsak Tiamkao, Suthipun Jitpimolmard, Verajit Chotmongkol, Elizabeth Barrett-Connor   +8 more
doaj   +1 more source

Multicenter, Retrospective Determination of the Clinical Utility of Screening Tests in Dogs With Immune‐Mediated Hemolytic Anemia in the United Kingdom and Ireland

Journal of Veterinary Internal Medicine, Volume 39, Issue 5, September/October 2025.
ABSTRACT Background Potential triggers of immune‐mediated hemolytic anemia (IMHA) are often identified, but their frequency and the benefit of extensive screening for these to individual dogs is uncertain. Objective To assess the frequency of non‐associative IMHA in dogs undergoing screening in Britain and Ireland and identify where specific tests ...
Tyler Morrison, Ioannis L. Oikonomidis, Hannah K. Walker, Nuno Sousa Santos, Sophie A. Conway, Benoît Cuq, Carolina S. C. Albuquerque, Claudia Gil‐Morales, Glynn Woods   +8 more
wiley   +1 more source

Angiostrongyliasis in the Americas [PDF]

, 2012
The helminth Angiostrongylus costaricensis Morera & Cespedes, 1971 is endemic to the Americas and is responsible for a pathological abdominal syndrome, caused by the presence of the adult helminth in the mesenteric arteries. This is microscopically characterized by eosinophilic infiltration, vascular abnormality and a granulomatous reaction ...
Arnaldo Maldonado, Raquel Simes, Silvana Thiengo   +2 more
openaire   +1 more source

Unexpected Shifts in Bivalve Function From Filtration to Transmission Risk

Freshwater Biology, Volume 70, Issue 6, June 2025.
ABSTRACT Understanding the complex interactions between filter‐feeding species and zoonotic disease transmission in aquatic environments is crucial for accurately quantifying the ecosystem services provided by these organisms. This study explores for the first time the roles of freshwater bivalves in the transmission dynamics of emerging zoonotic ...
Jakub Hradečný, Divakaran Pandian, Lucia Anettová, Anna Šipková, Juan Felipe Escobar‐Calderón, Mehrak Mohammadi, Kateřina Gregarová, David Modrý, Karel Douda   +8 more
wiley   +1 more source