Results 51 to 60 of about 30,523 (258)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Research on Spatial Location of a Spherical 3-RRR Parallel Mechanism

Jixie chuandong, 2019
The quaternion is used to represent the finite rotation of rigid body, and the finite rotation equation of rigid body is obtained. Based on the spherical 3-RRR parallel robot, an angular displacement sensor bracket is added to detect the attitude angle ...
Wang Li
doaj  

Single anchor node real-time positioning algorithm based on the antenna array

International Journal of Distributed Sensor Networks, 2017
This article presents an anchor node based on directional antenna array and reports the design of an automatic test system. The antenna radiation characteristics and the wireless channel model are studied first, followed by the evaluation of a single ...
Yong Fu
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Smart Tendon Actuated Flexible Actuator

Journal of Robotics, 2015
We investigate the kinematic feasibility of a tendon-based flexible parallel platform actuator. Much of the research on tendon-driven Stewart platforms is devoted either to the completely restrained positioning mechanism (CRPM) or to one particular type ...
Md. Masum Billah, Raisuddin Khan
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Feasibility and Accuracy of a Dual-Function AR-Guided System for PSI Positioning and Osteotomy Execution in Pelvic Tumour Surgery: A Cadaveric Study

Bioengineering
Objectives: Pelvic tumor resections demand high surgical precision to ensure clear margins while preserving function. Although patient-specific instruments (PSIs) improve osteotomy accuracy, positioning errors remain a limitation.
Tanya Fernández-Fernández, Javier Orozco-Martínez, Carla de Gregorio-Bermejo, Elena Aguilera-Jiménez, Amaia Iribar-Zabala, Lydia Mediavilla-Santos, Javier Pascau, Mónica García-Sevilla, Rubén Pérez-Mañanes, José Antonio Calvo-Haro   +9 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Angular Regularization for Positive-Unlabeled Learning on the Hypersphere

Trans. Mach. Learn. Res.
Positive-Unlabeled (PU) learning addresses classification problems where only a subset of positive examples is labeled and the remaining data is unlabeled, making explicit negative supervision unavailable. Existing PU methods often rely on negative-risk estimation or pseudo-labeling, which either require strong distributional assumptions or can ...
Vasileios Sevetlidis, George Pavlidis, Antonios Gasteratos   +2 more
openaire   +3 more sources