Results 101 to 110 of about 125,028 (275)

Navigating Nitration Chemistry: A Practical Guide to Reagents, Mechanisms, and Selectivity

Angewandte Chemie, EarlyView.
This review highlights key contributions of modern nitration chemistry, emphasizing sustainable mechanistic platforms and comparing the performance of both organic and inorganic reagents across aromatic, ipso‐, olefin, alkyne, and heteroatom nitration. It provides the community with a clearer, unified perspective on current advances and facilitates the
Harry Lecomte, Anthony J. Fernandes, Dmitry Katayev   +2 more
wiley   +2 more sources

Effects of Toxic Organic Compounds on Tenebrio molitor and Its Parasite Gregarina steini

Biology
Environmental pollution by toxic compounds affects various species of living organisms, their life cycles, and symbiotic relationships. This study investigated the host-parasite relationship between Tenebrio molitor Linnaeus, 1758 (Coleoptera ...
Denis Rybalka, Viktor Brygadyrenko
doaj   +1 more source

Molecular Characterization of Aniline Biodegradation by Some Bacterial Isolates having Unexpressed Catechol 2,3-Dioxygenase Gene

Journal of Pure and Applied Microbiology, 2018
Aromatic amines are potential mutagens and carcinogens, so biodegradation of them may protect our environment by safely getting rid of these compounds.
Fatma Mohlam, Walid Bakeer, Eman El-Gebaly, Magdy Amin   +3 more
doaj   +1 more source

Aggregation‐Induced Resonance Energy Transfer in Polymer Dots to Boost Electrochemiluminescence Performance for Bioimaging of Glycan on Cells

Advanced Science, EarlyView.
This study pioneers an aggregation‐induced resonance energy transfer mechanism by synergistically integrating aggregation‐induced emission (AIE), resonance energy transfer (RET), and thermally activated delayed fluorescence (TADF) within co‐reactant conjugated polymers to develop self‐enhanced ECL emitters, which achieves an ECL efficiency up to 92.6 ...
Chao Wang, Mengjiao Li, Yiran Li, Xiangfu Hu, Chunlan Li, Ningning Wang, Huangxian Ju   +6 more
wiley   +1 more source

Scalable Access to N‑Acylindole Linkages: Enabling the Synthesis of Antitrypanosomal Noncanonical Cyclic Peptides for Chagas Disease

Angewandte Chemie, EarlyView.
A gram‐scale supply of bulbiferamide A, which features a rare N‐acylindole linkage and possesses potent inhibitory activity against Trypanosoma cruzi epimastigotes (IC50 = 4.1 µM)—the causative parasite of Chagas disease—was successfully achieved. Moreover, the cyclization strategy developed in this study facilitated the synthesis of noncanonical ...
Jie Zhang, Hugh Nakamura
wiley   +2 more sources

1,2,6-thiadiazinones as novel narrow spectrum calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) inhibitors [PDF]

, 1983
We demonstrate for the first time that 4H-1,2,6-thiadiazin-4-one (TDZ) can function as a chemotype for the design of ATP-competitive kinase inhibitors. Using insights from a co-crystal structure of a 3,5-bis(arylamino)-4H-1,2,6-thiadiazin-4-one bound to ...
Asquith, Christopher R.M., Godoi, Paulo H., Counago, Rafael M., Laitinen, Tuomo, Scott, John W., Langendorf, Christopher G., Oakhill, Jonathan S., Drewry, David H., Zuercher, William J., Koutentis, Panayiotis A., Willson, Timothy M., Kalogirou, Andreas S.   +11 more
core   +3 more sources

Dual Effect of Steric Hindrance in Non‐Aqueous Amine Absorbents: Navigating the Trade‐Off Between Kinetics and Thermodynamics for Efficient CO2 Capture

Advanced Science, EarlyView.
This study elucidates how steric hindrance in amines creates a dual effect in CO2 capture: it thermodynamically favors the reaction by shifting the pathway from carbamate to alkyl carbonate formation, increasing capacity and lowering regeneration heat, while simultaneously slightly slowing the kinetics.
Xiaoyi Gao, Bin Xu, Xi Tang, Muyi Li, Cong Luo, Fan Wu, Xiaoshan Li, Liqi Zhang, Wen Chen   +8 more
wiley   +1 more source

Bis(silylene)‐Mediated N═N Bond Scission of Diazo Compounds

Angewandte Chemie, EarlyView.
The carborane‐based bis(silylene) enables unprecedented N═N bond scission in diazodiarylmethanes. While xanthene‐ and aniline‐based scaffolds promote end‐on addition with partial N═N activation, the carborane‐based variant uniquely achieves complete N═N bond scission of Ar2C═N═N compounds, resulting in isolable disilicon nitride imino species.
Yun Xiong, Shenglai Yao, Matthias Driess
wiley   +2 more sources

Synthesis and reactions of 4-(p-methoxybenzyl)-6-[5,6,7,8-tetrahydro-2-naphthyl]-pyridazin-3(2H)-one

Journal of the Serbian Chemical Society, 1999
The condensation of 4-(p-methoxybenzyl)-6-[5,6,7,8-tetrahydro-2-naphthyl]-pyridazin-3(2H)-one (3), prepared by the reaction of 6-[5,6,7,8-tetrahydro-2-naphthyl]-4,5-dihydropyridazin-3(2H)-one (1) and anisaldehyde, with dimethyl sulphate, formaldehyde and
NAGWA M.S. EL-DIN HARB
doaj  

Broad‐Spectrum Antimicrobial and Antibiofilm Activities of Halogenated Anilines Against Uropathogenic Escherichia coli and ESKAPE Pathogens

Microbial Biotechnology
Uropathogenic Escherichia coli (UPEC) is one of the leading causes of nosocomial infections and urinary tract infections (UTIs), capable of inducing a spectrum of conditions ranging from acute bladder cystitis to chronic pyelonephritis.
Bharath Reddy Boya, Jin‐Hyung Lee, Jintae Lee   +2 more
doaj   +1 more source