1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer +6 more
wiley +1 more source
Potent, Selective Pyrrolopyrimidine PDE11A4 Inhibitors with Improved Pharmaceutical Properties. [PDF]
Mahmood SU +10 more
europepmc +1 more source
Gold(I)‐Mediated Reactivity of Allenes With Mesoionic Nucleophiles: A Computational Exploration
The regioselective gold(I)‐mediated reactivity of allenes with mesoionic nucleophiles has been evaluated through computational analysis of the mechanisms involved. Instead of typical (3 + 2) pathways, sydnones and münchnones favour the formal (3 + 3) cyclizations affording substituted dihydropyridines.
Eduardo Garcia‐Padilla, Feliu Maseras
wiley +1 more source
Deaminative methylselenation of anlines with PhSO<sub>2</sub>SeCH<sub>3</sub>. [PDF]
Wang L +5 more
europepmc +1 more source
Effect of Acetaldehyde on P-Hydroxylation of Aniline by Aniline Hydroxylase
G, Kinoshita +4 more
openaire +2 more sources
Design, Synthesis, and Biological Evaluation of 2-Substituted Aniline Pyrimidine Derivatives as Potent Dual Mer/c-Met Inhibitors [PDF]
Daowei Huang +8 more
openalex +1 more source
A new series of structurally rich polyaromatic isonitriles is presented as photoredox catalysts. Their photophysical properties are investigated by UV–Vis absorption and fluorescence measurements, combined with experimental and theoretical studies to evaluate both ground‐ and excited‐state redox properties.
Cristina Martini +9 more
wiley +1 more source
Thermomechanical Behavior of Biobased Benzoxazine: Structure-Property Relationship and Role of Aromatic Side Groups. [PDF]
Khan MFZ, Abels G, Hartwig A, Koschek K.
europepmc +1 more source
A Rh(III)‐catalyzed [4 + 2] annulation of 2‐aryl imidazoles/benzimidazoles with α‐diazocarbonyl compounds is developed for the synthesis of π‐conjugated imidazo/benzimidazo[2,1‐a]isoquinolinones systems. Mechanistic studies and control experiment reveal that the reaction proceeds via imidazole‐directed ortho C(sp2)–H activation, followed by carbene C–H
Ganesh P. Pawar +4 more
wiley +1 more source
Machine learning-based QSAR modeling assay for the nitrification inhibition of 2,4,5-trichloroaniline-derived eco-friendly Schiff bases. [PDF]
Mondal T +9 more
europepmc +1 more source

