Results 241 to 250 of about 146,193 (341)

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer   +6 more
wiley   +1 more source

Potent, Selective Pyrrolopyrimidine PDE11A4 Inhibitors with Improved Pharmaceutical Properties. [PDF]

open access: yesACS Med Chem Lett
Mahmood SU   +10 more
europepmc   +1 more source

Gold(I)‐Mediated Reactivity of Allenes With Mesoionic Nucleophiles: A Computational Exploration

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The regioselective gold(I)‐mediated reactivity of allenes with mesoionic nucleophiles has been evaluated through computational analysis of the mechanisms involved. Instead of typical (3 + 2) pathways, sydnones and münchnones favour the formal (3 + 3) cyclizations affording substituted dihydropyridines.
Eduardo Garcia‐Padilla, Feliu Maseras
wiley   +1 more source

Effect of Acetaldehyde on P-Hydroxylation of Aniline by Aniline Hydroxylase

open access: yesJapanese Journal of Pharmacology, 1972
G, Kinoshita   +4 more
openaire   +2 more sources

Design, Synthesis, and Biological Evaluation of 2-Substituted Aniline Pyrimidine Derivatives as Potent Dual Mer/c-Met Inhibitors [PDF]

open access: gold
Daowei Huang   +8 more
openalex   +1 more source

Design, Synthesis, and Photophysical Studies of Functionalized Polyaromatic Isonitriles as Visible Light Photoredox Catalysts

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A new series of structurally rich polyaromatic isonitriles is presented as photoredox catalysts. Their photophysical properties are investigated by UV–Vis absorption and fluorescence measurements, combined with experimental and theoretical studies to evaluate both ground‐ and excited‐state redox properties.
Cristina Martini   +9 more
wiley   +1 more source

Rh(III)‐Catalyzed [4+2] Annulation of Imidazoles With α‐Diazocarbonyl Compounds: Direct Access to π‐Conjugated Imidazole‐Fused Isoquinolinone

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A Rh(III)‐catalyzed [4 + 2] annulation of 2‐aryl imidazoles/benzimidazoles with α‐diazocarbonyl compounds is developed for the synthesis of π‐conjugated imidazo/benzimidazo[2,1‐a]isoquinolinones systems. Mechanistic studies and control experiment reveal that the reaction proceeds via imidazole‐directed ortho C(sp2)–H activation, followed by carbene C–H
Ganesh P. Pawar   +4 more
wiley   +1 more source

Machine learning-based QSAR modeling assay for the nitrification inhibition of 2,4,5-trichloroaniline-derived eco-friendly Schiff bases. [PDF]

open access: yesRSC Adv
Mondal T   +9 more
europepmc   +1 more source

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