Results 161 to 170 of about 30,335 (240)

Towards sustainable pharmaceutical QC: micellar-UPLC strategy for concomitant analysis of a cardiovascular polypill with aniline and salicylic acid impurities. [PDF]

Sci Rep
Mohamed AR, Nour IM, Badrawy M, Darweish E.   +3 more
europepmc   +1 more source

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao, Jing Zhou, Jing Wang, Si‐Nan Zhao, Zhan‐Sheng Zhao, Qian Wang, Ya‐Nan Xie, Wei Jiao   +7 more
wiley   +1 more source

Orthorhombic polymorph of 4-(2,2':6',2''-terpyridin-4'-yl)aniline. [PDF]

IUCrdata
Edwards N, Zheng SL.
europepmc   +1 more source

Recent Advances in Conductive Rubber Composites: Progress, Challenges, and Emerging Opportunities

Macromolecular Rapid Communications, EarlyView.
This study reviews the recent advances in conductive rubber composites, focusing on key aspects such as material selection, conductive mechanisms, interfacial engineering, processing methods, vulcanization strategies, and practical applications. It also discusses current challenges and highlights emerging directions that are shaping the development of ...
Lu Yin, Ali Vahidifar, Steven Yu, Boxin Zhao   +3 more
wiley   +1 more source

Trifluoroacetic acid-mediated selective oxidation of arylamines to nitroarenes <i>via in situ</i> formed peroxytrifluoroacetic acid. [PDF]

RSC Adv
Li S, Wang L, Hu J, An Y, Huang J, Wen B, Dong Y, Li T, Chen X.   +8 more
europepmc   +1 more source

Bright Ferritin for Non‐Invasive MRI Monitoring of the Fate of Transplanted hPSC‐Cardiomyocytes in the Infarcted Rat Heart

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate that a recently reported bright ferritin magnetic resonance imaging (MRI) platform can track transplanted human pluripotent stem cell (hPSC)‐derived cardiomyocytes (hPSC‐CMs) longitudinally and on‐demand in the rat heart.
Keyu Zhuang, Faisal J. Alibhai, Beiping Qiang, Rocco Romagnuolo, Kyle D. W. Vollett, Bradley K. C. Freeman, M. Juliana Gomez‐Garcia, Tamilla Sadikov Valdman, Tameshwar Ganesh, Yu‐Qing Zhou, Hai‐Ying Mary Cheng, Michael A. Laflamme, Hai‐Ling Margaret Cheng   +12 more
wiley   +1 more source

Optimization of Hsp90/Aha1 Small-Molecule Disruptors Via the Evaluation of Amide Bioisosteres. [PDF]

ACS Med Chem Lett
Catalfano KC, Keegan BM, Blagg BSJ.
europepmc   +1 more source

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

ChemistryOpen, EarlyView.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda, Sami A. Al‐Hussain, Basant Farag, Mohamed El‐Naggar, Magdi E. A. Zaki, Emad S. A. Alhazmi, Adel S. M. Almohammadi, Sobhi M. Gomha   +7 more
wiley   +1 more source

Redundant ¹⁵N-Mediated <i>J</i>-Couplings Reveal an Aglycone Conformation in <i>N</i>-Phenyl Glycosylamines. [PDF]

J Org Chem
Habanová N, Kaminský J, Parkan K, Zýka J, Prouza V, Klepetářová B, Pohl R.   +6 more
europepmc   +1 more source