Results 81 to 90 of about 71,539 (307)

Printable Conductive Hydrogels for Electrochemical Biosensing and Soft Bioelectronic Interfaces

Advanced Science, EarlyView.
Flexible, conductive hydrogels that integrate printability, mechanical tunability, biocompatibility, and electronic performance remain challenging to achieve. Here, we develop 3D‐printable poly(ethylene glycol)–poly(pyrrole)‐ hydrogels with tissue‐like mechanics, high cytocompatibility, and robust electrochemical function.
Lukas Hein, Renan Colucci, Xin Wei, Tsvetomir Ivanov, Katharina Landfester, Ulrike Kraft, Maria Villiou   +6 more
wiley   +1 more source

Synthesis, characterization and biological evaluation of novel 2,5 substituted-1,3,4 oxadiazole derivatives

Saudi Pharmaceutical Journal, 2017
In the present study, a series of 3-(5-cyclohexyl-1,3,4-oxadiazol-2-yl)-N-substituted aniline have been synthesized by multistep reaction scheme. Benzohydrazide was used as the starting material.
Selvaraj Kavitha, Kulanthai Kannan, Sadhasivam Gnanavel   +2 more
doaj   +1 more source

Molecular connectivity indices for predicting bioactivities of substituted nitrobenzene and aniline compounds

Ecotoxicology and Environmental Safety, 2009
Bioconcentration and toxicity of 22 substituted nitrobenzene and aniline compounds to aquatic organisms were assessed with quantitative structure-activity relationship (QSAR). Acute toxicities of aquatic organisms, including daphnia (Daphnia pulex) and carp (Cyprinus carpio), to 22 chemicals have been determined in our previous work. In this study, the
Lin, K.H., Jaw, C.G., Yen, J.H., Wang, Y.S.   +3 more
openaire   +3 more sources

Lead identification and structure-activity relationships of heteroarylpyrazole arylsulfonamides as allosteric CC-chemokine receptor 4 (CCR4) antagonists [PDF]

, 2014
A knowledge-based library of aryl 2,3-dichlorophenylsulfonamides was synthesised and screened as human CCR4 antagonists, in order to identify a suitable hit for the start of a lead-optimisation programme.
Copley, R.C.B., Miah, A.H., O'Flynn, D., Percy, J.M., Procopiou, P.A.   +4 more
core   +1 more source

Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery

Advanced Science, EarlyView.
We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent
Zachary Rabinowitz, Riley J. Deutsch‐Williams, Ralph Weissleder   +2 more
wiley   +1 more source

Coupled treatment of aniline and phenol in water by electrochemical copolymerization

Water Science and Technology
Anilines and phenols are recognized as challenging organic pollutants in industrial wastewater. Herein, the coupled treatment of aniline and phenol in water was achieved through electrochemical oxidation-induced copolymerization.
Xiuyun Li, Yue Tian, Hongxiang Di, Wenzhong Yang, Yahui Wang, Lifang Tian   +5 more
doaj   +1 more source

Automated analysis of oxidative metabolites [PDF]

, 1974
An automated system for the study of drug metabolism is described. The system monitors the oxidative metabolites of aromatic amines and of compounds which produce formaldehyde on oxidative dealkylation.
Furner, R. L.
core   +1 more source

Directed Evolution Improves the Catalytic Efficiency of APEX2‐Mediated Proximity‐Dependent RNA Labeling

Advanced Science, EarlyView.
ABSTRACT Engineered ascorbate peroxidase APEX2 has been widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin‐aniline (Btn‐An) remains suboptimal. To overcome this limitation, we performed yeast surface display‐based directed evolution to enhance APEX2 ...
Gang Wang, Yi Li, Peiyuan Meng, Peng Zou
wiley   +1 more source

Development of a fluorogenic small substrate for dipeptidyl peptidase-4

Beilstein Journal of Organic Chemistry, 2017
A series of aniline and m-phenylenediamine derivatives with electron-withdrawing 3,3,3-trifluoropropenyl substituents were synthesized as small and chemically stable fluorescent organic compounds.
Futa Ogawa, Masanori Takeda, Kanae Miyanaga, Keita Tani, Ryuji Yamazawa, Kiyoshi Ito, Atsushi Tarui, Kazuyuki Sato, Masaaki Omote   +8 more
doaj   +1 more source

Recent Advances in the Synthetic and Mechanistic Aspects of the Ruthenium-catalyzed Carbon-heteroatom Bond Forming Reactions of Alkenes and Alkynes [PDF]

, 2011
The group’s recent advances in catalytic carbon-to-heteroatom bond forming reactions of alkenes and alkynes are described. For the C–O bond formation reaction, a well-defined bifunctional ruthenium-amido catalyst has been successfully employed for the ...
Yi, Chae S.
core   +2 more sources