Results 11 to 20 of about 3,108,804 (226)

An efficient synthesis of furan-3(2H)-imine scaffold from alkynones

open access: yesRoyal Society Open Science, 2021
A novel efficient method to generate spiro furan-3(2H)-imine derivatives is established by the reaction between the α,β-unsaturated ketones and aniline derivatives.
Anas J. Rasras   +4 more
doaj   +1 more source

Data on synthesis and characterization of new p-nitro stilbene Schiff bases derivatives as an electrochemical DNA potential spacer

open access: yesData in Brief, 2020
The structural investigation of synthesized compounds can be carried out by various spectroscopic techniques. It is an important prospect in order to elucidate the structure of the desired products before being further utilized.
Nur Zafirah Mohd Izham   +9 more
doaj   +1 more source

Synthesis of N1-(3,5-Bis(trifluoromethyl)benzyl)benzene-1,2-diamine and N,N-Bis(2-nitrophenyl)-3,5-bis(trifluoromethyl)aniline

open access: yesMolbank, 2023
A monosubstituted benzene-1,2-diamine building block, N1-(3,5-bis(trifluoromethyl)benzyl)benzene-1,2-diamine, was prepared in two steps from commercially available 3,5-bis(trifluoromethyl)benzylamine and 1-fluoro-2-nitrobenzene, while the use of 3,5-bis ...
Luka Ciber   +5 more
doaj   +1 more source

Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair and p53. [PDF]

open access: yes, 2013
The antitumor prodrug Temozolomide is compromised by its dependence for activity on DNA mismatch repair (MMR) and the repair of the chemosensitive DNA lesion, O6-methylguanine (O6-MeG), by O6-methylguanine-DNA-methyltransferase (EC 2.1.1.63, MGMT). Tumor
Arris C. E.   +42 more
core   +1 more source

EVALUATION OF THE INHIBITORY EFFECTIVENESS OF THREE FERROCENE DERIVATIVES FOR CORROSION OF STEEL XC70 BY SPECTROSCOPY OF ELECTROCHEMICAL IMPEDANCE

open access: yesJournal of Fundamental and Applied Sciences, 2015
In this work, we studied the efficacy of corrosion inhibition of carbon steel X70 in HCl 1M solution using ferrocenyl compounds prepared in VPRS laboratory, these compounds are: N-(férrocenyl méthyl)-2-nitro aniline(Fc12), N-(férrocenyl méthyl)-3-nitro ...
O. Rahim   +4 more
doaj   +1 more source

Synthesis and Identification of Some New Derivative of Trimethoprim and Paracetemol Drugs

open access: yesمجلة بغداد للعلوم, 2013
In this research two series of the new derivatives of Trimethoprim and paracetamol drugs have been prepared which known as a high medicinal effectiveness.
Baghdad Science Journal
doaj   +1 more source

2-Substituted Aniline as a Simple Scaffold for LuxR-Regulated QS Modulation

open access: yesMolecules, 2017
The ability of the 2-substituted aniline motif to serve as a scaffold for designing potential LuxR-regulated quorum sensing (QS) modulators has been investigated, using docking experiments and biological evaluation of a series of 15 specially synthesized
Sizhe Li   +3 more
doaj   +1 more source

New Benzoxazole Derivatives as Antiprotozoal Agents: In Silico Studies, Synthesis, and Biological Evaluation

open access: yesJournal of Chemistry, 2021
Background. Benzoxazole derivatives have different biological activities. In pursuit of designing novel chemical entities with antiprotozoal and antimicrobial activities, benzoxazolyl aniline was utilized as a privileged scaffold of a series of (3 ...
Mohamed A. Abdelgawad   +12 more
doaj   +1 more source

Precursor-Directed Biosynthesis of Aminofulvenes: New Chalanilines from Endophytic Fungus Chalara sp.

open access: yesMolecules, 2021
The plant endophyte Chalara sp. is able to biotransform the epigenetic modifier vorinostat to form unique, aniline-containing polyketides named chalanilines. Here, we sought to expand the chemical diversity of chalaniline A-type molecules by changing the
Mahsa Khoshbakht   +4 more
doaj   +1 more source

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