3D-printed devices for continuous-flow organic chemistry [PDF]
, 2013 We present a study in which the versatility of 3D-printing is combined with the processing advantages of flow chemistry for the synthesis of organic compounds.
Cronin, Leroy +4 more
core +6 more sources
Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair and p53. [PDF]
, 2013 The antitumor prodrug Temozolomide is compromised by its dependence for activity on DNA mismatch repair (MMR) and the repair of the chemosensitive DNA lesion, O6-methylguanine (O6-MeG), by O6-methylguanine-DNA-methyltransferase (EC 2.1.1.63, MGMT). Tumor
Arris C. E. +42 more
core +1 more source
Novel ionization reagent for the measurement of gas-phase ammonia and amines using a stand-alone atmospheric pressure gas chromatography (APGC) source. [PDF]
, 2020 RationaleContaminants present in ambient air or in sampling lines can interfere with the target analysis through overlapping peaks or causing a high background. This study presents a positive outcome from the unexpected presence of N-methyl-2-pyrrolidone,
Finlayson-Pitts, Barbara J +3 more
core +1 more source
Synthesis and Identification of Some New Derivative of Trimethoprim and Paracetemol Drugs
مجلة بغداد للعلوم, 2013 In this research two series of the new derivatives of Trimethoprim and paracetamol drugs have been prepared which known as a high medicinal effectiveness.
Baghdad Science Journal
doaj +1 more source
2-Substituted Aniline as a Simple Scaffold for LuxR-Regulated QS Modulation
Molecules, 2017 The ability of the 2-substituted aniline motif to serve as a scaffold for designing potential LuxR-regulated quorum sensing (QS) modulators has been investigated, using docking experiments and biological evaluation of a series of 15 specially synthesized
Sizhe Li +3 more
doaj +1 more source
Pot, atom and step economic (PASE) synthesis of highly functionalized piperidines: a five-component condensation [PDF]
, 2007 The diastereoselective pot, atom and step economic (PASE) synthesis of highly functionalized piperidines has been realized. The procedure simply involves mixing methyl acetoacetate, 2 equiv of aldehyde and 2 equiv of aniline together in the presence of ...
Clarke, Paul A. +2 more
core +1 more source
Molecules, 2021 The plant endophyte Chalara sp. is able to biotransform the epigenetic modifier vorinostat to form unique, aniline-containing polyketides named chalanilines. Here, we sought to expand the chemical diversity of chalaniline A-type molecules by changing the
Mahsa Khoshbakht +4 more
doaj +1 more source
Journal of Chemistry, 2021 Background. Benzoxazole derivatives have different biological activities. In pursuit of designing novel chemical entities with antiprotozoal and antimicrobial activities, benzoxazolyl aniline was utilized as a privileged scaffold of a series of (3 ...
Mohamed A. Abdelgawad +12 more
doaj +1 more source
Synthetic chemistry and biological activity of pentafluorosulphanyl (SF5) organic molecules [PDF]
, 2012 Acknowledgements We thank the European Commission for financial support (Industry Academia Partnerships and Pathways project “PET BRAIN”, Contract No 251482). S.A.
Altomonte, Stefano, Zanda, Matteo
core +1 more source
Journal of Analytical Methods in Chemistry, 2012 An electrochemical study of two water-soluble aniline derivatives, N-(3-sulfopropyl) aniline (AnPS) and N-(3-sulfopropyl) p-aminodiphenylamine (DAnPS), in aqueous acidic electrolytic solutions containing different kinds of doping anions (Cl −, SO4 2 ...
Loredana Vacareanu +2 more
doaj +1 more source