Results 131 to 140 of about 384,323 (292)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Animal-Assisted Interventions: Factors Affecting Donkey Behaviours and Attitude Toward Humans
AnimalsThe relationship between humans and donkeys has ancient origins. In recent years, donkeys’ involvement in Animal-Assisted Intervention (AAI) has grown, raising major concerns about their welfare during these activities.
Serenella d’Ingeo +6 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Editorial: Human-Animal Interaction (HAI) Research: A Decade of Progress
Frontiers in Veterinary Science, 2020 Sandra McCune +7 more
doaj +1 more source
Pet Therapy Use in Pediatric Hospitals: an Internet Based Pilot Study [PDF]
, 2004 Introduction: In a technologically advanced health care system, health care providers continue to care for the physical, emotional, and spiritual well being of their patients.
Potter, Kara
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Veterinary science : humans, animals and health [PDF]
, 2011 This living book is a collection of open access materials bringing scientific papers to a humanities ...
Fudge, Erica, Palmer, Clare
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Farmer Consumer Partnerships: Information search and decision making - the case of ethical values of organic products [PDF]
, 2009 The CORE Organic pilot project ‘Farmer Consumer Partnerships’ aims at analysing and testing innovative communication strategies of organic companies with respect to ethical values as a means of reconnecting organic farmers and consumers against the ...
Hamm, Ulrich, Zander, Katrin
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source