Results 101 to 110 of about 223,666 (304)

Early postnatal caloric restriction protects adult male intrauterine growth-restricted offspring from obesity. [PDF]

open access: yes, 2012
Postnatal ad libitum caloric intake superimposed on intrauterine growth restriction (IUGR) is associated with adult-onset obesity, insulin resistance, and type 2 diabetes mellitus (T2DM).
Dai, Yun   +6 more
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The phenolic complex in flaxseed [PDF]

open access: yes, 2008
Flaxseed is the richest plant source of the lignan secoisolariciresinol diglucoside (SDG). In flaxseed, SDG exists in an oligomeric structure with 3-hydroxy-3-methyl glutaric acid (HMGA) forming a phenolic complex together with p-coumaric acid and ...
Strandås, Christina
core  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Temporal Segmentation of Surgical Sub-tasks through Deep Learning with Multiple Data Sources [PDF]

open access: yes, 2020
Many tasks in robot-assisted surgeries (RAS) can be represented by finite-state machines (FSMs), where each state represents either an action (such as picking up a needle) or an observation (such as bleeding).
Aghajani Pedram, Sahba   +6 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Animal-assisted therapy (AAT) - a review of current scientific research

open access: yesQuality in Sport
Animal-assisted therapy (AAT) is an adjunctive therapeutic method that uses purposeful human-animal interaction in the treatment process. Systematic literature reviews and randomized controlled trials from the last few years (2015-2025) demonstrate that
Maciej Bieniek   +8 more
doaj   +1 more source

The Effect of Interaction with Therapy Horses on University Students\u27 Perceived Stress Level [PDF]

open access: yes, 2017
This research project investigates how university students are affected by interacting with therapy horses. Stress is the factor that will be evaluated in this particular study.
Chapman, Alexa
core   +2 more sources

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