Results 211 to 220 of about 6,379,052 (242)

Barriers to Maternal Presence at the Bedside of Infants With Neonatal Opioid Withdrawal Syndrome. [PDF]

Cureus
Guth A, Gangemi-Hanninen A, Divatia H.
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Comparative Evaluation of Depth of Irrigant Penetration Using Different Irrigation Systems: An In Vivo Study. [PDF]

Cureus
Ohm A, Manan R, Mishra P, Chauhan B, Gutti AB, Soni A.   +5 more
europepmc   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Anti-PD1 immunotherapy in MHC-I dysregulated head and neck cancer promotes metastasis via CD8⁺ T-cell insufficiency. [PDF]

Signal Transduct Target Ther
Chakraborty AK, Choudhury C, Raut RD, Bais MV.   +3 more
europepmc   +1 more source

Employer-Sponsored Fertility and Family-Building Benefits Among 928 U.S. Employers. [PDF]

Cureus
Baloch KF, Saghar V, Gulati R.
europepmc   +1 more source

Hemodynamic Outcomes of Anesthesia Management Assisted by Nurses Trained in Specific Medical Acts in Gastrointestinal Surgery: A Retrospective Propensity Score-Matched Pilot Study. [PDF]

Cureus
Kumagai N, Sugawara T.
europepmc   +1 more source

Responsible Ownership and Welfare Indicators for Dogs and Cats in Rural Lithuania: Self-Reported Practices and In-Person Assessment. [PDF]

Animals (Basel)
Ramanauskaitė EM, Malakauskienė S, Šukytė T, Malakauskas A.   +3 more
europepmc   +1 more source

Companion animals and mental health: a narrative synthesis of how pets deliver therapeutic mechanisms outside formal provision. [PDF]

Front Psychiatry
Vicary E, Rogers A, Brooks H.
europepmc   +1 more source