Results 41 to 50 of about 146,853 (284)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Animal-assisted therapy using dogs: The benefits to children [PDF]
Includes bibliographical ...
Oian, Corrine E.
core
Costs, benefits and mechanisms of animal-assisted therapy: adopting a change in perspective
Animal-assisted therapy has progressed in recent years, helping a broad spectrum of people to tackle stress, loneliness and health problems, including those with life-long disabilities.
Vanessa A. D. Wilson
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Animal-Assisted Therapy Supports Student Connectedness [PDF]
Animal-assisted therapy is a complementary approach to supporting the well-balanced student. In particular, therapy dogs in school can have a direct impact on students’ social interactions, class participation, and behavior, as well as strengthening ...
Jill Fedor
core +1 more source
Feasibility of Animal-Assisted Therapy in the Treatment of Depression
The objective of this review is to assess the potential inclusion of animal-assisted therapy practices in the treatment of depression. Given the documented rise in the incidence of depression in recent years, there is a recognized significance in ...
Onour Impram, Fatima Zehra Allahverdi
doaj +1 more source
Healing smiles: Enhancing pediatric dental care through animal-assisted therapy – A narrative review
Dental anxiety refers to the negative emotional response of fear or avoiding dental care, which is exhibited by cognitive, physiological, and motor reactions when related to dental visits or dental treatment.
Aishwarya Vineshkumar Antala +1 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Furry Therapists: the advantages and disadvantages of implementing animal therapy [PDF]
Includes bibliographical ...
Schultz, Erin E.
core
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source

