Structural insights into glycan recognition by plant immune receptors: a comparative perspective with animal innate immune systems. [PDF]
Vílchez-Pinto G +4 more
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Elevation-dependent productivity trade-offs in wild <i>Elymus sibiricus</i> populations across the Qinghai-Tibet Plateau zone. [PDF]
Niu YL, Qin Y.
europepmc +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
The association between animal‑based and plant‑based protein intake with sleep quality, mood, anxiety, depression and stress among elderly: a cross-sectional study. [PDF]
Ghosn B +3 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Interactions Between Plant Proteins and Gut Microbiota as Determinants of Intestinal Health. [PDF]
Szydłowska A +2 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Neural signature of human-dog interactions: EEG correlates from comparisons with plant and replica dog in a within-subject, cross-over randomized trial. [PDF]
Carbone F, Martin-Grieder C, Hediger K.
europepmc +1 more source
UK marginal cost curves for the agriculture, forestry, land-use and land-use change sector out to 2022 and to provide scenario analysis for possible abatement options out to 2050 – RMP4950. [PDF]
Barnes, Andrew +11 more
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