Results 121 to 130 of about 6,674,194 (312)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Multi‐Species Canopy Latrines in Costa Rican Cloud Forests: A Mammal Interactions Hub in a Single Tree Species

Ecology and Evolution
We report the discovery of arboreal multi‐species mammal latrines in montane cloud forests of Costa Rica. We surveyed 169 trees from 29 species. Canopy multi‐species latrines were only found in 11 individuals of a single tree species, Ficus tuerckheimii.
Jeremy Quirós‐Navarro, Tim Chamberlain, Deiver Espinoza   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Rewiring of the jasmonic acid signaling pathway during insect herbivory on Arabidopsis [PDF]

, 2011
Plants are attacked by a plethora of potentially devastating pathogens and pests. To protect themselves, plants have evolved a sophisticated immune system in which phytohormones play pivotal regulatory roles.
Sub Plant-Microbe Interactions, Plant Microbe Interactions, Verhage, A.   +2 more
core  

Comparative metagenomic analysis of gut microbiota in Anacanthotermes turkestanicus and A. ahngerianus reveals diet- and habitat-driven functional divergence

Frontiers in Insect Science
The gut microbiome of termites plays a crucial role in lignocellulose degradation and nutrient recycling. This study presents the first metagenomic characterization of the gut microbiota in two lower termite species, Anacanthotermes ahngerianus and ...
Ulugbek Togaev, Ulugbek Togaev, Vartika Mathur, Vartika Mathur, Aziza Rakhmonkulova, Surbhi Agarwal, Aarav Mathur, Shuhrat Turageldiyev, Rasul Ruzmetov, Abboskhon S. Turaev, Zaitjan Tillyabaev, Alimjan Matchanov, David Sillam-Dussès   +12 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Status of induced resistance in plant bacterial host-parasite interactions

, 2005
Induced resistance as a new phenomenon in the biological control against bacterial plant diseases is presented as a review on the last 15 years' research on this aspect.
Zeller, Wolfgang
core  

Signaling in Arabidopsis roots in response to beneficial rhizobacteria [PDF]

, 2012
Root colonization by selected strains of beneficial soil-resident bacteria is known to improve plant growth, influence root system architecture and trigger a systemic immune response that is effective against a broad range of pathogens, known as induced ...
Zamioudis, C, Sub Plant-Microbe Interactions, Plant Microbe Interactions   +2 more
core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source