Results 51 to 60 of about 151,749 (266)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Data on visitation records from wild bees and plants along a land use gradient in Germany and Belgium: laboratory work and protocol description for barcodingBiodiversity Exploratories

Data in Brief
The dataset contains information on plant-bee interactions in an agricultural landscape with diverse intensities of land use management, in Germany and Belgium.
Maria Alejandra Parreño, Susanne Werle, Louella Buydens, Joshua Spitz, Franz Härtl, Jeremias Montoya, Fabian Ruedenauer, Baturalp Arisoy, Regina Seiler, Clementine Leroy, Qingming Feng-Spitz, Carmen Alexandra Nebauer, Andrea Ferrari, Nicolas Proessl, Ragna Borchardt, Birte Peters, Stefanie Siebler, Matthias Reese, Nils Schumacher, Tuyen Phung, Katharina Schildt, Jessica Ebensberger, Maximilian Seiler, Philipp Reiter, Stephanie Beelaert, Marius Buydens, Sumeer Koirala, Jerome Moreniere, Rene Tänzler, Cedric Alaux, Michał Filipiak, Ivan Meeus, Niels Piot, Michael Kuhlmann, Fabrice Requier, Alexandra Klein, Jean Luc Brunet, Mickael Henry, Alexander Keller, Sara Diana Leonhardt   +39 more
doaj   +1 more source

Receptors and Signaling Pathways for Recognition of Bacteria in Livestock and Crops: Prospects for Beneficial Microbes in Healthy Growth Strategies

Frontiers in Immunology, 2018
Modern animal and crop production practices are associated with the regular use of antimicrobials, potentially increasing selection pressure on bacteria to become resistant. Alternative approaches are needed in order to satisfy the demands of the growing
Julio Villena, Julio Villena, Haruki Kitazawa, Haruki Kitazawa, Saskia C. M. Van Wees, Corné M. J. Pieterse, Hideki Takahashi, Hideki Takahashi   +7 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Cropping System Conversion led to Organic Carbon Change in China’s Mollisols Regions

Scientific Reports, 2017
Land use change driven by diet, globalization, and technology advancement have greatly influenced agricultural production and environment in the mollisols region of China, with a marked impact on the depletion of soil organic matter, a signature property
Yuxin Tong, Jianguo Liu, Xiaolin Li, Jing Sun, Anna Herzberger, Dan Wei, Weifeng Zhang, Zhengxia Dou, Fusuo Zhang   +8 more
doaj   +1 more source

STABILITY ANALYSIS OF ECOLOGICAL MODELS OF PLANT-ANIMAL INTERACTIONS IN RIPARIAN ZONES [PDF]

Proceedings on Engineering Sciences
The research summarizes the essential findings and open topics from previous stability analyses of models involving Riparian zones. These models are central to tropic interactions, ecological complexity, and species coexistence.
Ravi Kiran Duvvuri , Rami Reddy Bhavanam , G. V. Ramana , Venkat Rao Kanuri   +3 more
doaj   +1 more source