Results 111 to 120 of about 4,920,066 (261)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Animal Health News

open access: yes
This internet resource contains issues published throughout multiple yearsHighly Pathogenic Avian Influenza(HPAI) in Livestock -- How can dairy producers help?
Kansas Animal Health
core  

Modification of the gasless fetoscopy technique for the treatment of large myelomeningocele: a study in sheep [PDF]

open access: yesEinstein (São Paulo), 2010
Objective: To change the gasless fetoscopy technique in order to reduce the diameter of entry orifices in the myometrium. Methods: Seven pregnant ewes were submitted to fetoscopy for repairing a large skin defect measuring 4.0 x 3.0 cm, created in the ...
Denise Araujo Lapa Pedreira   +5 more
doaj  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Caring hands discussions by the Laboratory Animal Refinement & Enrichment Forum

open access: yes, 2010
This book is a collection of electronic discussions that took place on the Animal Welfare Institute's Laboratory Animal Refinement & Enrichment Forum between June 2007 and March 2010.
Animal Welfare Institute   +1 more
core  

Animal cognition and animal minds [PDF]

open access: yes, 1997
Psychology, according to a standard dictionary definition, is the science of mind and behavior. For a major part of the twentieth century, (nonhuman) animal psychology was on a behavioristic track that explicitly denied the possibility of a science of ...
Allen, Colin
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Small animal dermatology : a color atlas and therapeutic guide /

open access: yes, 2011
Designed with busy practitioners and students in mind, Small Animal Dermatology: A Color Atlas and Therapeutic Guide provides concise, thorough coverage of over 250 skin diseases affecting small animals. More than 1,000 high-quality images help to ensure
Medleau, Linda.Small animal dermatology.   +1 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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