Results 91 to 100 of about 2,928,935 (339)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Handling the dry-off problem in organic dairy herds by teat sealing or homeopathy com-pared to therapy omission [PDF]

open access: yes, 2006
Avoiding antibiotics is one of the crucial goals in organic dairy herd health management. Thus, a trial with 102 cows (408 quarters) was conducted to com-pare 2 common medical dry-off practices in organic dairying, internal teat sealant (Orbeseal ...
Heil, Fritz   +4 more
core  

Effective methods for population control in dogs and cats in the municipality of Salinópolis, Pará

open access: yesPubvet
In Brazil, the population of dogs and cats is growing exponentially, causing adverse public and environmental health problems. The multiplication of these stray animals results in an increase in abandonment and mistreatment, also facilitating the ...
Agnes Maynara de Oliveira   +9 more
doaj   +1 more source

Effects of sheltering on behavior and fecal corticosterone level of elderly dogs

open access: yesFrontiers in Veterinary Science, 2016
In Japan, the human population is aging rapidly, and the abandonment of dogs by the elderly people who have died or been hospitalized becomes a problem. It is hypothesized that elderly dogs have difficulty adapting to the novel circumstances when brought
Katsuji Uetake   +3 more
doaj   +1 more source

Alternative agricultural policy scenarios, sector modelling and indicators - A sustainability assessment [PDF]

open access: yes, 2004
In this article, we assess ecological, economic and social sustainability impacts of four alternative agricultural policy scenarios relevant to the European perspective.
Aakkula, Jyrki   +2 more
core  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Children and Pets: The Hidden Victims of Domestic Violence & Abuse (DVA): Where Action & Activism merge! [PDF]

open access: yes, 2019
Children and Pets: The Hidden Victims of Domestic Violence & Abuse (DVA): Where Action & Activism merge! Researchers such as Harne (2011) and Radford et al (2011) have long championed the area of Children’s rights in the DVA field and the Government ...
McKie, Ruth, Turgoose, Di
core  

AGRICULTURAL CHANGE IN THE RUSSIAN GRAIN BELT: A CASE STUDY OF SAMARA OBLAST

open access: yesGeography, Environment, Sustainability, 2012
Change in agricultural land use in Samara Oblast is analyzed on the basis of agricultural statistics, field observations, and satellite imagery. Besides the general decline in animal husbandry, three drivers of spatial change are uncovered—accessibility ...
Kirsten de Beurs   +2 more
doaj   +1 more source

Loneliness: A Concept Analysis [PDF]

open access: yes, 2008
TOPIC. Loneliness is a universal human experience recognized since the dawn of time, yet it is unique for every individual. Loneliness can lead to both depression and low self‐esteem. PURPOSE. This article explicates the concept of loneliness through the
Bekhet, Abir K.   +1 more
core   +1 more source

Home - About - Disclaimer - Privacy