Results 71 to 80 of about 2,928,935 (339)
Animals, 2019 Cruelty- and neglect-related canine welfare concerns are important welfare and social issues. Dog breed has been identified as a risk factor for bad welfare, and yet its role in different types of canine welfare concerns has not been fully investigated ...
Hao Yu Shih +2 more
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basic and Applied EcologyAgriculturally marginal grasslands have been traditionally managed at low intensity for centuries and are among Europe’s key biodiversity hotspots. Because of their low profitability, many of them have been either abandoned or subjected to intensified ...
Susanna Hempel +4 more
doaj +1 more source
The psychosocial impact of assistive device scale: Italian validation in a cohort of nonambulant people with neuromotor disorders [PDF]
, 2018 The importance of adaptive seating system on body structure and function is widely accepted, but its impact on psychosocial aspects needs more consideration by health professionals. This article describes the Italian validation of the Psychosocial Impact
Candeloro, C +7 more
core +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Comparison of two plant functional approaches to evaluate natural restoration along an old-field-deciduous forest chronosequence [PDF]
, 2009 Question: Are direct and indirect trait-based approaches similar in their usefulness to synthesize species responses to successional stages?\ud Location: Northern hardwood forests, Que´bec, Canada\ud (451010–451080N; 731580–741210W).\ud Methods: Two ...
Aubin, Isabelle +4 more
core +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Should Dogs and Cats be Given as Gifts? [PDF]
, 2013 Policies that state pets should not be adopted as gifts are prevalent at animal welfare organizations, despite the fact that this belief is unfounded. Denying adopters who intend to give the animals as gifts may unnecessarily impede the overarching goal ...
Emily D. Dolan +4 more
core +2 more sources
ENVIRONMENTAL SYSTEMS RESEARCH, 2002 兵庫県神戸市北区山田町藍那地区に多数分布する放棄ため池のうち, 56ヵ所において、2000年夏期と2001年冬期に, それぞれ水棲生物の捕獲調査を行い, 生息種および生息密度と、ため池周辺環境との関連性について解析した。その結果、樹木等によってため池上空が被覆され, その開放率が低下するに伴い, アメリカザリガニの捕獲される割合が増加するという結果力得られた。また, アメリカザリガニの生息密度および生息の有無について検討したところ, ため池の地理的な分布位置によって、それらが大きく異なることが明らかになった。このような偏った分布特性は、過去におけるアメリカザリガニの分布域拡大過程の影響を受けているものと考察された。
Hiroyuki YAMADA +4 more
openaire +2 more sources