Results 181 to 190 of about 108,798 (245)

Cell therapy comparison of dental pulp stem cells, hepatocytes, and their exosomes for liver fibrosis treatment in rats

open access: yesAnimal Models and Experimental Medicine, EarlyView.
DPSCs, hepatocytes, and exosomes were tested for liver fibrosis therapy. Exosome‐based treatment exhibited superior antioxidative and regenerative effects. Liver enzymes, oxidative stress, and profibrotic markers were significantly reduced. α‐SMA, desmin, and related gene expression were downregulated.
Sahar Rahimi   +3 more
wiley   +1 more source

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat   +5 more
wiley   +1 more source

Abuse potential assessment of novel central nervous system active and psychedelic substances for controlled substances act scheduling recommendations. [PDF]

open access: yesJ Psychopharmacol
Henningfield JE   +15 more
europepmc   +1 more source

The Causes of Animal Abuse:

Theoretical Criminology, 1998
This article draws on the leading crime theories and the limited research on animal abuse to present a theory that explains why individuals engage in animal abuse. First, I describe the immediate determinants of animal abuse. Animal abuse is said to result from ignorance about the abusive consequences of our behavior for animals, the belief that abuse
Robert Agnew
exaly   +2 more sources

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