An umbrella review of the evidence for equine‐assisted interventions
Objective To establish the evidence base for animal‐assisted interventions, and specifically, hippotherapy and other interventions involving horses, in the context of improving biological, physical, psychological and social functioning, and outcomes in ...
Cindy Stern, Anna Chur‐hansen
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Animal‐assisted interventions: making better use of the human‐animal bond [PDF]
In the third of Veterinary Record 's series of articles promoting One Health, Daniel Mills and Sophie Hall discuss the therapeutic effects of companion animals, the influence of pets on childhood development and how researchers are elucidating the true value of animal companionship.
Daniel Mills, Sophie Hall
openaire +3 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Background The number of adolescents hospitalized with mental health problems, which are vulnerable and under a stressful situation, has increased in the last years.
Maylos Rodrigo-Claverol +9 more
doaj +1 more source
Animal-assisted interventions: Possibilities and limitations of implementation in young persons with developmental disabilities and behavioral disorders [PDF]
The type of complementary treatment under the interdisciplinary term Animal-assisted interventions - AAI implies all types of interventions which integrate a variety of animals within two key modalities: Animal-Assisted Activities - AAA and Animal ...
Milanović-Dobrota Biljana
doaj
A Social-Emotional Learning Program for Suicide Prevention through Animal-Assisted Intervention
The aim of the study was to carry out a pilot implementation and evaluation of the OverCome-AAI program, a pioneering program for the prevention of suicidal behavior through animal-assisted interventions for young people with high risk factors for ...
Alexander Muela +7 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The Effect of Dog Presence on the Therapeutic Alliance: A Systematic Review
The development of a therapeutic alliance represents one of the most important processes that occurs in psychological therapy and is one of the strongest predictors of treatment outcome. To ensure the effective delivery of psychological interventions, it
Timothy Collier +3 more
doaj +1 more source

