Results 31 to 40 of about 1,595,028 (249)

Trends of Animal Bite Cases and Comparison of Cases Reported during Pre-COVID-19 and COVID-19 Period in a Dedicated Anti-Rabies Clinic from a Tertiary Care Hospital, Hassan, Karnataka, India: A Retrospective Cohort Study [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Rabies causes 100% case fatality in animal bite victims if left untreated, and it ranks as the 10th leading cause of death due to infectious diseases worldwide.
G Praveen, KJ Subhashini, KJ Shashank, M Ashik   +3 more
doaj   +1 more source

Bush Animal Attacks: Management of Complex Injuries in a Resource-Limited Setting. [PDF]

, 2011
Though animal-related injuries and fatalities have been documented throughout the world, the variety of attacks by wild animals native to rural East Africa are less commonly described.
Kotecha Vihar R, Chandika Alphonce, Kotecha, Vihar R, Chandika, Alphonce, Mitchell Katrina B, Mitchell, Katrina B   +5 more
core   +1 more source

Re-exposure animal bite management among incident animal bite cases in a secondary care Hospital in Delhi, India

Indian Journal of Public Health, 2020
Complete postexposure prophylaxis with 4 doses of anti-rabies vaccine (ARV) in a previously vaccinated (nonnaïve) individual results in administration of two extra ARV doses resulting in wastages of precious resources comprising vaccine logistics, human ...
Saurav Basu, Warisha Mariam, Sahadev Santra, Suneela Garg, Rajiv Singhal   +4 more
doaj   +1 more source

Adherence to the post-exposure prophylaxis among animal bite patients attending rabies clinic at tertiary care hospital – A cross-sectional study

Asian Journal of Medical Sciences
Background: Rabies is an acute and 100% fatal viral disease transmitted to humans through the bite or lick of an infected animal. It can be successfully prevented if a complete course of anti-rabies vaccine (ARV) is taken following an animal bite.
Shivasharan HN , Chaitra Ramesh Chavan , Neeta PN , Sameena ARB , Suresh CM , Ramesh K , Ananthachari KR   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Clinical study on rabies prone animal bite

, 2018
Introduction: Rabies is almost invariably fatal zoonotic disease, it can be prevent well with proper management of wound and rabies prophylaxis. This study aims to describe the pattern of rabies prone animal bite, to observe the trends of management and ...
Sheikh Mohammad Noor E Alam, Mohammad Mahfuzul Hoque, Farhana Akter, MA Faiz, Robed Amin, BUM Wahid Ahmed   +5 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The Burden of Rabies in Tanzania and Its Impact on Local\ud Communities [PDF]

, 2013
Rabies remains a major public health threat in many parts of the world and is responsible for an estimated 55,000 human deaths annually. The burden of rabies is estimated to be around US$20 million in Africa, with the highest financial expenditure being ...
Katie Hampson, Ferguson, H., Ferguson, Heather, Simon, C., Hampson, K., Maganga Sambo, Cleophas Simon, Hampson, Katie, Sarah Cleavel, Urassa Honorati, Urassa, H., Lembo, T., Honorati Urassa, Lembo Tiziana, Cleaveland, S., Ferguson Heather, Sambo Maganga, Lembo, Tiziana, Sambo, Maganga, Urassa, Honorati, Tiziana Lembo, Simon Cleophas, Simon, Cleophas, Hampson Katie, Cleaveland, Sarah, Sambo, M., Sarah Cleaveland, Heather Ferguson, Cleaveland Sarah   +28 more
core   +1 more source