Results 91 to 100 of about 1,256,762 (303)
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Agricultural software : a case study of feed and animal information systems in the New Zealand dairy industry : a thesis presented in partial fulfilment of the requirements of a Masters of AgriCommerce at Massey University, Palmerston North, New Zealand [PDF]
, 2017 Every farmer utilises agricultural software, either directly or indirectly, as part of feed and animal information systems (IS) used for decision making and compliance on New Zealand (NZ) dairy farms.
Hammond, Hamish
core
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Theories of the development of human communication [PDF]
, 2013 This article considers evidence for innate motives for sharing rituals and symbols from animal semiotics, developmental neurobiology, physiology of prospective motor control, affective neuroscience and infant communication. Mastery of speech and language
Delafield-Butt, Jonathan +1 more
core
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Towards a Wearer-Centred Framework for Animal Biotelemetry [PDF]
, 2016 The emerging discipline of Animal-Computer Interaction (ACI) aims to understand the relation between animals and technology in naturalistic settings, to design technology that can support animals in different contexts and to develop user-centred research
Mancini, Clara +2 more
core
Exorcising Grice’s ghost : an empirical approach to studying intentional communication in animals [PDF]
, 2017 Language’s intentional nature has been highlighted as a crucial feature distinguishing it from other communication systems. Specifically, language is often thought to depend on highly structured intentional action and mutual mindreading by a communicator
Bickel, Balthasar +23 more
core +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Overcoming bias in the comparison of human language and animal communication. [PDF]
Proc Natl Acad Sci U S A, 2023 Cartmill EA.
europepmc +1 more source