Results 221 to 230 of about 2,325,542 (385)

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Yeast Culture Supplementation Improves Meat Quality by Enhancing Immune Response and Purine Metabolism of Small-Tail Han Sheep (<i>Ovis aries</i>). [PDF]

Int J Mol Sci
Bai X, Wang L, Sun H, Sun L, An J, Fu S, Zhao M, Liu F, Ren X, Liu Z, He J, Liu Y.   +11 more
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

An introductory undergraduate course covering animal cell culture techniques [PDF]

, 2004
Paul Mozdziak, James N. Petitte, Susan D. Carson   +2 more
openalex   +1 more source

Concerted conservation actions to support chimpanzee cultures. [PDF]

Philos Trans R Soc Lond B Biol Sci
Wessling EG, Whiten A, Soiret SK, Scholfield K, Samuni L, Rutz C, Redmond I, Pintea L, Lanjouw A, Koops K, Kamgang SA, Kalan AK, Ikemeh RA, Humle T, Hobaiter C, Frisch-Nwakanma H, Freymann E, Doumbe O, Brakes P, Abwe E, Sanz C.   +20 more
europepmc   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Laboratory Culture of the Sepiolid Squid Euprymna scolopes: A Model System for Bacteria-Animal Symbiosis

, 1997
Roger T. Hanlon, Michael F. Claes, S. E. Ashcraft, Paul V. Dunlap   +3 more
openalex   +2 more sources

Rapid and Specific Detection ofSalmonellaspp. in Animal Feed Samples by PCR after Culture Enrichment [PDF]

, 2004
Charlotta Löfström, Rickard Knutsson, Charlotta Engdahl Axelsson, Peter Rådström   +3 more
openalex   +1 more source

A Systematic Review and Meta-Analysis on the Presence of <i>Escherichia coli</i> O157:H7 in Africa from a One Health Perspective. [PDF]

Microorganisms
Somda NS, Adesoji TO, Tetteh-Quarcoo PB, Donkor ES.   +3 more
europepmc   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source