Results 241 to 250 of about 2,258,380 (360)

A simple inland culture system provides insights into ascidian post-embryonic developmental physiology. [PDF]

Open Biol
Mathiesen BT, Ohta M, Magalhaes BP, Castelletti C, Perria V, Schuster K, Christiaen L, Ohta N.   +7 more
europepmc   +1 more source

Idiopathic Pulmonary Fibrosis Caused by Damaged Mitochondria and Imbalanced Protein Homeostasis in Alveolar Epithelial Type II Cell

Advanced Biology, EarlyView.
By systematizing a large body of evidence and propose a cascade relationship between protein homeostasis, endoplasmic reticulum stress, mitochondrial dysfunction, and pro‐fibrotic factor, providing a theoretical basis for ATII cells dysfunction as a possible pathophysiological initiating event for idiopathic pulmonary fibrosis.
Zhaoxiong Dong, Xiaolong Wang, Peiwen Wang, Mingjian Bai, Tianyu Wang, Yanhui Chu, Yan Qin   +6 more
wiley   +1 more source

Establishment of an experimental model of canine apocrine gland anal sac adenocarcinoma organoid culture using a three-dimensional culture method. [PDF]

Sci Rep
Nagashima Y, Yamamoto H, Elbadawy M, Ishihara Y, Tsurukami I, Abugomaa A, Kaneda M, Yamawaki H, Usui T, Sasaki K.   +9 more
europepmc   +1 more source

Neuroprotective and Neurorescue Effects of a Novel Polymeric Nanoparticle Formulation of Curcumin (NanoCurc™) in the Neuronal Cell Culture and Animal Model: Implications for Alzheimer's disease [PDF]

, 2011
Balmiki Ray, Savita Bisht, Amarnath Maitra, Anirban Maitra, Debomoy K. Lahiri   +4 more
openalex   +1 more source

Mucus Physically Restricts Influenza A Viral Particle Access to the Epithelium

Advanced Biology, EarlyView.
The infectious potential of respiratory viruses depends on their ability to navigate through a layer of mucus that serves as a protective barrier in the lung. It is demonstrated that influenza A virus penetration through mucus is significantly limited by the gel's internal microstructure and, to a lesser extent, by adhesive binding to mucin glycans ...
Logan Kaler, Elizabeth M. Engle, Maria Corkran, Ethan Iverson, Allison Boboltz, Maxinne A. Ignacio, Taj Yeruva, Margaret A. Scull, Gregg A. Duncan   +8 more
wiley   +1 more source

Advancing humanized 3D tumor modeling using an open access xeno-free medium. [PDF]

Front Toxicol
Malakpour-Permlid A, Rodriguez MM, Zór K, Boisen A, Oredsson S.   +4 more
europepmc   +1 more source

Generation of Advanced Blood–Brain Barrier Spheroids Using Human‐Induced Pluripotent Stem Cell‐Derived Brain Capillary Endothelial‐Like Cells

Advanced Biology, EarlyView.
In this article, the establishment and characterization of a self‐assembled 3D BBB spheroid model using human induced pluripotent stem cell (hiPSC)‐derived and primary cells is reported. Spheroids demonstrate in‐vivo like tight junction ultrastructure and, in comparison to 2D mono‐cultures, higher transcript expression of BBB specific genes.
Sanjana Mathew‐Schmitt, Sabrina Oerter, Evelin Reitenbach, Sabine Gätzner, Alevtina Höchner, Heinz‐Georg Jahnke, Jörg Piontek, Winfried Neuhaus, Andreas Brachner, Marco Metzger, Antje Appelt‐Menzel   +10 more
wiley   +1 more source

Deep culturing the fecal microbiota of healthy laying hens. [PDF]

Anim Microbiome
Feng Z, Lorenc N, O'Brien B, Sun G, Li Z, Jung D, Ronholm J.   +6 more
europepmc   +1 more source

Considering the Risks and Costs of Solid Organ Xenotransplantation

Advanced Biology, EarlyView.
This perspective discusses the rationale, risks, and costs of whole‐organ xenotransplantation. It considers alternative strategies to obviate the demand for transplants and optimize allotransplantation systems and practices that do not impose xenotransplantation's harms and risks, and whether they are the most ethical and effective means to increase ...
Catharine E. Krebs, Janine McCarthy, Kristie Sullivan, James Craner, Brendan Parent, Ann Lam   +5 more
wiley   +1 more source

Humanising nanotoxicology: replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard. [PDF]

Front Bioeng Biotechnol
Fraser R, Campbell K, Pokorski P, MacKinnon E, McAllister K, Neves KB, Murphy F.   +6 more
europepmc   +1 more source