Results 101 to 110 of about 1,485,253 (263)

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Experimental Animal Models in Respiratory Diseases

Düzce Tıp Fakültesi Dergisi
Respiratory diseases are among the leading causes of morbidity and mortality worldwide. Various animal models are used to understand the pathogenesis of these diseases and develop novel therapeutic strategies.
Pınar Yıldız Gülhan
doaj   +1 more source

Editorial: Regulation of Mitochondrial Function on Animal Diseases. [PDF]

Front Vet Sci, 2022
Zhang H, Chang YF, Liu J.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Venereal Diseases of Animals [PDF]

Sexually Transmitted Infections, 1937
openaire   +2 more sources

Beyond accuracy: leveraging ASSURED criteria for field evaluation of point-of-care tests for food animal diseases. [PDF]

Front Vet Sci, 2023
Ochwo S, Perez AM, Pérez Aguirreburualde MS.   +2 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An Overview of Transboundary Animal Diseases of Viral Origin in South Asia: What Needs to Be Done? [PDF]

Vet Sci, 2022
Gongal G, Rahman H, Thakuri KC, Vijayalakshmy K.   +3 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Editorial: Proceedings of the 3rd ISESSAH Conference 2019

Frontiers in Veterinary Science, 2021
Dustin L. Pendell, Thomas L. Marsh, Bouda Vosough Ahmadi, Didier Raboisson, Henk Hogeveen, Jonathan Rushton   +5 more
doaj   +1 more source