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FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Expert views on European research needs regarding emerging infectious animal diseases: results of a Delphi study [PDF]
, 2010 Frewer, L.J., Wentholt, M.T.A.
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Hormone Research in Paediatrics, 2009
<i>Background:</i> Several endocrine disorders that affect humans also occur as endocrinopathies in companion animals. Spontaneous endocrine disorders in animals may provide valuable information for their counterparts in human endocrinology. For example, the discovery of progesterone-induced growth hormone production in the mammary gland of
Kooistra, H.S. +3 more
openaire +3 more sources
<i>Background:</i> Several endocrine disorders that affect humans also occur as endocrinopathies in companion animals. Spontaneous endocrine disorders in animals may provide valuable information for their counterparts in human endocrinology. For example, the discovery of progesterone-induced growth hormone production in the mammary gland of
Kooistra, H.S. +3 more
openaire +3 more sources
2012
Prion diseases occur in many animal species, most notably in ruminants. While scrapie in sheep has been recognised for three centuries and goat scrapie has been recognised for decades, BSE in cattle is a relatively novel disease which was first diagnosed in the UK in the mid 1980s.
Otto, Windl, Mike, Dawson
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Prion diseases occur in many animal species, most notably in ruminants. While scrapie in sheep has been recognised for three centuries and goat scrapie has been recognised for decades, BSE in cattle is a relatively novel disease which was first diagnosed in the UK in the mid 1980s.
Otto, Windl, Mike, Dawson
openaire +2 more sources
Veterinary Record, 2007
SIR, — At last, the Government has recognised the importance of monitoring diseases in wild animals ( VR , July 21, 2007, vol 161, pp 74-75). defra must be congratulated. As long ago as the 1950s, some of us in the profession were concerned about zoonoses and diseases of wild animals ...
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SIR, — At last, the Government has recognised the importance of monitoring diseases in wild animals ( VR , July 21, 2007, vol 161, pp 74-75). defra must be congratulated. As long ago as the 1950s, some of us in the profession were concerned about zoonoses and diseases of wild animals ...
openaire +2 more sources
The Annals of Occupational Hygiene, 1994
Experimental inhalation in a number of studies has demonstrated that chrysotile asbestos can cause pulmonary fibrosis and both benign and malignant pulmonary tumours, two lesions which are associated in that the studies reporting high tumour rates also found high levels of asbestosis.
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Experimental inhalation in a number of studies has demonstrated that chrysotile asbestos can cause pulmonary fibrosis and both benign and malignant pulmonary tumours, two lesions which are associated in that the studies reporting high tumour rates also found high levels of asbestosis.
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Seminars in Musculoskeletal Radiology, 2002
Rickets is a metabolic bone disorder characterized by osteopenic changes resulting from the failure of calcification of the osteoid matrix and absent mineralization of hypertrophic cartilage cells at the epiphyseal growth plates in growing primates, herbivores, swine, carnivores, and birds.
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Rickets is a metabolic bone disorder characterized by osteopenic changes resulting from the failure of calcification of the osteoid matrix and absent mineralization of hypertrophic cartilage cells at the epiphyseal growth plates in growing primates, herbivores, swine, carnivores, and birds.
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The Impact of Diseases on the Importation of Animals and Animal Products
Annals of the New York Academy of Sciences, 2000Abstract: For decades the veterinary services of the united states and other nations protected Their Livestock and poultry industries from the ravages of introduced animal diseases by rigorous import restrictions. this policy of zero risk frequently translated to no or reduced trade in animals and animal products or dramatic trade inequities. however,
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