Results 281 to 290 of about 1,298,457 (333)

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Assessing proton plans with three different beam delivery systems versus photon plans for head and neck tumors

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To compare plan quality among photon volumetric modulated arc therapy (VMAT) and intensity‐modulated proton therapy (IMPT) with robustness using three different proton beam delivery systems with various spot size (σ) ranges: cyclotron‐generated proton beams (CPBs) (σ: 2.7–7.0 mm), linear accelerator proton beams (LPBs) (σ: 2.9–5.5 mm),
Tara Gray   +9 more
wiley   +1 more source

A review of artificial intelligence in brachytherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen   +4 more
wiley   +1 more source

Bone‐wise rigid registration of femur, tibia, and fibula for the tracking of temporal changes

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Multiple myeloma (MM) induces temporal alterations in bone structure, such as osteolytic bone lesions, which are challenging to identify through manual image interpretation. The large variation in radiologists' assessments, even at expert centers, further complicates diagnosis.
Arttu Ruohola   +5 more
wiley   +1 more source

Assessing the rigidity of thermoplastic masks for head immobilization effectiveness in stereotactic radiosurgery

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract This study compared three Brainlab thermoplastic masks—Cranial 4pi basic, stereotactic (Close Mask V2), and open‐face—to see how well they limited head movement during Stereotactic Radiosurgery (SRS). Using a head phantom, we tested rotational movements (pitch, yaw, and roll) and measured displacements with the ExacTrac system.
Iris Pasion Apale   +2 more
wiley   +1 more source

Stereotactic radiosurgery for multiple small brain metastases using gamma knife versus single‐isocenter VMAT: Normal brain dose based on lesion number and size

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The study evaluates rapid linear accelerator (Linac) single isocenter stereotactic radiosurgery (SRS) with Hyperarc for large target numbers. We compared to Gamma Knife (GK), which suffers from long treatment times and investigated causes of differences. Methods Linac SRS and GK treatment plans for patients receiving 18 Gy to the gross
Abram Abdou   +4 more
wiley   +1 more source

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