Results 51 to 60 of about 1,328,750 (347)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker +7 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Conceptual foundations for a clarified meaning of the 3Rs principles in animal experimentation
Animal WelfareRussell and Burch’s 1959 original definitions of the 3Rs (replacement, reduction and refinement) are widely used today as standards for the ethical use of non-human animals in research, although they have a number of limitations. Authors and institutions
Edwin Louis-Maerten +4 more
doaj +1 more source
Revival of Ancient Questions: Current Developments in Theological Animal Ethics
Acta Universitatis Carolinae Theologica, 2023 Since the middle of the 19th century, animal husbandry has been industrialised and subdued to economic efficiency to an unsurpassable degree. Animals as living beings and fellow creatures have largely fallen by the wayside.
Michael Rosenberger
doaj +1 more source
Animal Geographies III: Ethics [PDF]
, 2015 ArticleCopyright © 2015 by SAGE PublicationsThere is no animal geography without ethics. The very coupling of the words gives rise to an ethical endeavor; an acceptance that animals have a geography, a making visible of animals within our human geography
Buller, HJ
core +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
A Novel Method of Assessing Floor Friction in Cowsheds and Its Association with Cow Health
Animals, 2019 Measurement of friction of cowshed floors to determine slipperiness potential is important for cow comfort. Existing methods require elaborate equipment and procedures. A quick method for assessment of friction characteristics is proposed.
Arvind Sharma +2 more
doaj +1 more source
An Ethics Toolkit to Support Animal-Centered Research and Design [PDF]
, 2022 Luisa Ruge, Clara Mancini
openalex +1 more source
Animal-Computer Interaction: a Manifesto (2011) and sections from Towards an Animal-Centred Ethics for Animal-Computer Interaction (2016) [PDF]
, 2016 Reprint of journal article "Animal-Computer Interaction: a Manifesto" (2011) and of sections of journal article "Towards an Animal-Centred Ethics for Animal-Computer Interaction ...
Mancini, Clara
core
Environmental ethics for business sustainability [PDF]
, 2011 The paper derives operational principles from environmental ethics for business organizations in order to achieve sustainability. Business affects the natural environment at different levels.
Zsolnai, László
core +1 more source