Results 61 to 70 of about 4,974,799 (302)
Noninvasive extendable prosthesis: a new design
The treatment of choice for distal femur malignancies in skeletally immature patients remains controversial. As the mainstream treatment, limb-salvage treatment has been recently investigated, but its application in children remains challenging ...
Jie Zhang +4 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
126 pagesAnnual Report of the Minnesota Veterinary Diagnostic LaboratoryUniversity of Minnesota. Agricultural Experiment Station. (1991). Animal Health in Minnesota.
University of Minnesota. Agricultural Experiment Station
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Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
124 pagesAnnual Report of the Minnesota Veterinary Diagnostic Laboratory- 1996University of Minnesota. Agricultural Experiment Station. (1998). Animal Health in Minnesota.
University of Minnesota. Agricultural Experiment Station
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Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Curcumin reduces the pathogenicity of Streptococcus suis serotype 2 in mice by targeting suilysin
Background: Streptococcus suis (S. suis) is a significant zoonotic pathogen, with serotype 2 (SS2) being the most prevalent. Suilysin (SLY), an essential toxin indicator for S. suis, is crucial in the infections caused by SS2.
Jiafei Zhan +13 more
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Fattening steers in winter. Fattening lambs in winter
This archival publication may not reflect current scientific knowledge or recommendations. Current information available from University of Minnesota Agricultural Experiment Station: http://www.maes.umn.edu/Shaw, Thomas; University of Minnesota. Division
Shaw, Thomas +1 more
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