Results 251 to 260 of about 357,418 (307)

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

Advanced Science, EarlyView.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang, Wanxiang Niu, Yuanfei Wang, Peng Chen, Maolin Mu, Xiaoming Zhang, Ben Xu, Shanshan Hu, Chaoshi Niu, Pengfei Wu   +9 more
wiley   +1 more source

Increasing canopy cover elevates vehicle collision risk for barbastelle bats (Barbastella barbastellus) at roads. [PDF]

Sci Rep
O'Malley KD, Schofield HW, Wright PGR, Hargreaves D, Corcoran AJ, Mathews F.   +5 more
europepmc   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Novel 3D Scanning and Multi-Angle Analysis Uncover the Ontogenetic Developmental Dynamics of the Skull in <i>Vespertilio sinensis</i>. [PDF]

Biology (Basel)
Li X, Bao M, Chang Y, Wang H, Feng J.
europepmc   +1 more source

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

Advanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li, Huiyang Huang, Cunhao Hu, Xuan Zhang, Song Lin, Xiaodan Huang, Ti‐fei Yuan, Kwok‐Fai So, Lu Huang, Chaoran Ren, Qian Tao   +10 more
wiley   +1 more source

The structure of the annual migratory flight activity in a songbird. [PDF]

Proc Biol Sci
Sjöberg S, Macías-Torres P, Andersson A, Bäckman J, Thorup K, Tøttrup AP, Alerstam T.   +6 more
europepmc   +1 more source

Drone-based application of whale tags: A "tap-and-go" approach for scientific animal-borne investigations. [PDF]

PLoS One
Vogt DM, Pagani S, Gonzalez-Peltier Z, Gero S, Gruber DF, Wood RJ.   +5 more
europepmc   +1 more source

Using Advanced Tri-Axial Accelerometer Data to Improve Behavioral Time Budgets and Bioenergetic Estimates of Wintering Lesser Scaup. [PDF]

Ecol Evol
Schley HL, Williams CK, Homyack J, Harvey B, Olsen GH, Johnson S.   +5 more
europepmc   +1 more source

Aerobatic maneuvers in insect-scale flapping-wing aerial robots via deep-learned robust tube model predictive control. [PDF]

Sci Adv
Hsiao YH, Tagliabue A, Matteson O, Kim S, Zhao T, How JP, Chen Y.   +6 more
europepmc   +1 more source

Helicoverpa zea selected on Bt corn have wing shapes better suited to long distance flight. [PDF]

Environ Entomol
Mikac KM, Dominguez Davila JH, Powley MJ, Barclay S, Pezzini D, Reisig DD.   +5 more
europepmc   +1 more source