Results 231 to 240 of about 27,577,089 (399)

Assessment of Nociception and Inflammatory/Tissue Damage Biomarkers in a Post-COVID-19 Animal Model. [PDF]

Int J Mol Sci
Sánchez-Robles EM, Rodríguez-Rivera C, Paniagua Lora N, Herradón Pliego E, Goicoechea Garcia C, Arendt-Nielsen L, Fernández-de-Las-Peñas C, López-Miranda V.   +7 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Efficacy of sulfonamides targeting malic enzyme in an animal model of Chagas disease. [PDF]

Front Pharmacol
Dos Santos TCF, da Silva RB, de Sousa IL, Naciuk FF, Marchese L, Eufrásio AG, Lobo-Rojas AE, Giampauli RM, de Souza VB, Schenka AA, Bruder M, Rocco SA, Cordeiro AT.   +12 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Focused ultrasound-enhanced nose-to-brain delivery of a therapeutic antibody in a large-animal model. [PDF]

Theranostics
Fadera S, Boas CAWV, Yue Y, Gu Z, Yuan J, De D, Rogers BE, Nazeri A, Chen H.   +8 more
europepmc   +1 more source

Towards the evaluation in an animal disease model: Fluorinated 17β-HSD1 inhibitors showing strong activity towards both the human and the rat enzyme

, 2015
Ahmed S. Abdelsamie, Emmanuel Bey, Emanuele M. Gargano, Chris J. van Koppen, Martin Empting, Martin Frotscher   +5 more
openalex   +1 more source

Automated classification of otitis media with OCT: augmenting pediatric image datasets with gold-standard animal model data

, 2022
Guillermo L. Monroy, Jungeun Won, Jindou Shi, Malcolm C. Hill, Ryan G. Porter, Michael Novák, Wenzhou Hong, Pawjai Khampang, Joseph E. Kerschner, Darold R. Spillman, Stephen A. Boppart   +10 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Animal models of addiction: Compulsive drug taking and cognition

, 2019
Jean Lud Cadet
openalex   +2 more sources

A novel animal model to investigate fractionated radiotherapy-induced alimentary mucositis: the role of apoptosis, p53, nuclear factor-κB, COX-1, and COX-2 [PDF]

, 2007
Ann S. J. Yeoh, Rachel J. Gibson, Eric E. K. Yeoh, Joanne M. Bowen, Andrea M. Stringer, Kar Giam, Dorothy Keefe   +6 more
openalex   +1 more source