Results 241 to 250 of about 3,851,825 (350)

The mouse pale ear pigment mutant as a possible animal model for human platelet storage pool deficiency [PDF]

, 1981
EK Novak, S. W. Hui, RT Swank
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Animal Model Screening for Hyperlipidemic ICR Mice. [PDF]

Int J Mol Sci
Chen X, Zhou Y, Yang J, Yang R, Xue S, Wang Q, Niu W.   +6 more
europepmc   +1 more source

Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies

Molecular Oncology, EarlyView.
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová, Hana Svozilová, Marcela Krzyžánková, Radim Sonnek, Anastasiya Volakhava, Anastasia Smirnova, Tatiana Grigoreva, Zuzana Jašková, Hana Synáčková, Dennis Wahl, Michaela Bilčíková, Libor Červinek, Šárka Pospíšilová, Ilgar Mamedov, Karla Plevová   +14 more
wiley   +1 more source

Assessment of Lumbar Vertebrae L1-L7 and Proximal Femur Microstructure in Sheep as a Large Animal Model for Osteoporosis Research. [PDF]

Biology (Basel)
Camassa JA, Barros VV, Babo PS, Pereira FAM, Morais JJL, Fertuzinhos A, Azevedo JT, Reis RL, Gomes ME, Martins-Bessa A, Viegas CA, de Freitas SH, Dourado N, Dias IR.   +13 more
europepmc   +1 more source

Approximation of Prediction Error Variance in Large-Scale Animal Models

, 1988
I. Misztal, G.R. Wiggans
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Harnessing animal model and computational experiments to discover antidiabetic compounds in Ficus racemosa. [PDF]

BMC Complement Med Ther
Hossain MU, Rahman ABZN, Hossain MS, Dey S, Chowdhury ZM, Bhattacharjee A, Ahammad I, Hasan MK, Ahmed I, Hosen MB, Das KC, Keya CA, Salimullah M.   +12 more
europepmc   +1 more source

Model animals and their applications [PDF]

Science China Life Sciences, 2015
openaire   +3 more sources