Results 321 to 330 of about 26,422,673 (403)

Tree shrew as a new animal model for musculoskeletal disorders and aging. [PDF]

Bone Res
Wei X, Li H, Qiu J, Jiao J, Guo X, Yin G, Yang P, Han Y, Zhao Q, Zeng H, Rao Z, Gao X, Li K, Lai P, Zhang S, Yang C, Lu D, Bai X.   +17 more
europepmc   +1 more source

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

Experimental Infection of Ferrets with <i>Bartonella henselae</i>: In Search of a Novel Animal Model for Zoonotic Bartonellosis. [PDF]

Pathogens
Lashnits E, Robveille C, Neupane P, Richardson T, Linder K, McKeon G, Maggi R, Breitschwerdt EB.   +7 more
europepmc   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

FEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

An animal model of severe acute respiratory distress syndrome for translational research. [PDF]

Lab Anim Res
Chu KA, Lai CY, Chen YH, Kuo FH, Chen IY, Jiang YC, Liu YL, Ko TL, Fu YS.   +8 more
europepmc   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Role of Extracellular Vesicles in Chronic Post-Embolic Pulmonary Hypertension: Data from an Experimental Animal Model and Patients. [PDF]

Biomedicines
Mendoza-Zambrano E, Sánchez-López V, Gómez-Rodríguez B, García-Lunar I, Pereda-Arnau D, Jara-Palomares L, Elías-Hernández T, García-Álvarez A, Otero-Candelera R.   +8 more
europepmc   +1 more source

Endogenous animal spirits and investment an agent-based model [PDF]

Fontana Magda, Marchionatti Roberto
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