d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada+3 more
wiley +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Effect of Fangxia-Dihuang Decoction on doxorubicin-induced cognitive impairment in breast cancer animal model. [PDF]
Wang X+5 more
europepmc +1 more source
Earthing effects on mitochondrial function: ATP production and ROS generation
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source
Development and validation of BCG vaccine-induced novel granulomatous liver injury preclinical animal model. [PDF]
Sharma S+8 more
europepmc +1 more source
Digital pathology assessment of kidney glomerular filtration barrier ultrastructure in an animal model of podocytopathy. [PDF]
Laudon A+13 more
europepmc +1 more source
Genomic-transcriptomic analysis identifies the Syrian hamster as a superior animal model for human diseases. [PDF]
Wang C+30 more
europepmc +1 more source
Improving the robustness and efficiency of cell sheet protocol for breast cancer induction in animal model: A Geltrex plus Gelatin approach. [PDF]
Alshareeda AT+10 more
europepmc +1 more source
Pharmacokinetic Interaction Between Olaparib and Regorafenib in an Animal Model. [PDF]
Szkutnik-Fiedler D+9 more
europepmc +1 more source
Gastric greater curvature plication combined with Nissen fundoplication compared to sleeve gastrectomy in patients with obesity and animal model. [PDF]
Cao C+7 more
europepmc +1 more source