Results 51 to 60 of about 1,294,311 (264)

Standard operating procedures (SOP) in experimental stroke research: SOP for middle cerebral artery occlusion in the mouse [PDF]

, 2012
Recently, systematic reviews have found quantitative evidence that low study quality may have introduced a bias into preclinical stroke research. Monitoring, auditing, and standard operating procedures (SOPs) are already key elements of quality control ...
Members of the MCAO-SOP Group, Ulrich Dirnagl   +1 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Concepts, examples and discussion of influencing factors [PDF]

, 2019
Monitoring and surveillance of antimicrobial usage in animals is a public health concern and different methods are currently discussed widely in public, science and politics.
Merle, Roswitha, Meyer‐Kühling, Borris   +1 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Controlling risks of pathogen transmission by flies on organic pig farms - A review [PDF]

, 2007
Fly prevention and control on animal production units is necessary to prevent the transmission of pathogens that could affect animal and human health and the maintenance of good hygiene.
Kijlstra, Prof dr A, Meerburg, Dr. BG, Vermeer, MSc., HM   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Epigenetic biomarkers for animal welfare monitoring

Frontiers in Veterinary Science, 2023
Biomarkers for holistic animal welfare monitoring represent a considerable unmet need in veterinary medicine. Epigenetic modifications, like DNA methylation, provide important information about cellular states and environments, which makes them highly ...
Rose Whelan, Sina Tönges, Florian Böhl, Frank Lyko   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Feed nutritional composition affects the intestinal microbiota and digestive enzyme activity of black soldier fly larvae

Frontiers in Microbiology, 2023
IntroductionUsing black soldier fly larvae (BSFLs) to treat food waste is one of the most promising environmental protection technologies.MethodsWe used high-throughput sequencing to study the effects of different nutritional compositions on the ...
Guozhong Chen, Guozhong Chen, Guozhong Chen, Kai Zhang, Kai Zhang, Kai Zhang, Wenli Tang, Wenli Tang, Youzhi Li, Junyi Pang, Xin Yuan, Xin Yuan, Xiangbin Song, Xiangbin Song, Linlin Jiang, Linlin Jiang, Linlin Jiang, Linlin Jiang, Xin Yu, Xin Yu, Xin Yu, Xin Yu, Hongwei Zhu, Hongwei Zhu, Hongwei Zhu, Hongwei Zhu, Jiao Wang, Jiao Wang, Jiao Wang, Jianlong Zhang, Jianlong Zhang, Jianlong Zhang, Jianlong Zhang, Xingxiao Zhang, Xingxiao Zhang, Xingxiao Zhang, Xingxiao Zhang   +36 more
doaj   +1 more source

Integrated community profiling indicates long-term temporal stability of the predominant faecal microbiota in captive cheetahs [PDF]

, 2015
Understanding the symbiotic relationship between gut microbes and their animal host re- quires characterization of the core microbiota across populations and in time.
Becker, Anne, Hesta, Myriam, Huys, Geert, Janssens, Geert, Snauwaert, Cindy   +4 more
core   +4 more sources