Results 41 to 50 of about 438,882 (262)
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows +19 more
wiley +1 more source
Linking behavioral states to landscape features for improved conservation management
A central theme for conservation is understanding how animals differentially use, and are affected by change in, the landscapes they inhabit. However, it has been challenging to develop conservation schemes for habitat‐specific behaviors.
Maitreyi Sur +10 more
doaj +1 more source
Animal movements in fire‐prone landscapes
ABSTRACTMovement is a trait of fundamental importance in ecosystems subject to frequent disturbances, such as fire‐prone ecosystems. Despite this, the role of movement in facilitating responses to fire has received little attention. Herein, we consider how animal movement interacts with fire history to shape species distributions.
Dale G. Nimmo +26 more
openaire +4 more sources
ABSTRACT Background Germ cell tumors (GCTs) often arise in the ovaries and testes (extracranial) but can also develop in the brain (intracranial). We examined the relationship of individual, family, and community‐level socioeconomic status (SES) with stage of disease at diagnosis in a cohort of pediatric patients with GCT from Children's Oncology Group
Heydon K. Kaddas +7 more
wiley +1 more source
Evaluating population connectivity and targeting conservation action for an endangered cat
Dispersal of animals among populations helps to increase genetic variability and population viability. The endangered ocelot (Leopardus pardalis) in south Texas persists in two small populations separated by 30 km and cutoff from populations in ...
Sarah E. Lehnen +3 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Evaluating the use of marine protected areas by endangered species: A habitat selection approach
1. Optimizing the design of marine protected area (MPA) networks for the conservation of migratory marine species and their habitats involves a suite of important considerations, such as appropriate scale requirements and the distribution of ...
Kelsey E. Roberts +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A fundamental goal of ecology is to understand the spatial distribution of species. For moving animals, their location is crucially dependent on the movement mechanisms they employ to navigate the landscape.
Jonathan R. Potts
doaj +1 more source

