Results 141 to 150 of about 879,291 (289)

Increased reproductive output in stereotypic captive Rhabdomys females: Potential implications for captive breeding.

open access: yes, 2010
Captive animal populations can diverge considerably from populations in the wild, despite the animals not being deliberately domesticated. If the phenotypes which are of benefit in captivity are heritable, the genotypes of captive-stock can diverge ...
Jones, M.   +3 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Song sharing and repertoire change as indicators of social structure in the Noisy Scrub-bird

open access: yes, 2007
The Endangered Noisy Scrub-bird is a small passerine that is seldom seen but often heard in its range on the south coast of Western Australia. The difficulties in observing this cryptic bird mean that little is known about its social system.
Berryman, Abby N.
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Animal welfare assessment through smartphone applications : challenges and opportunities

open access: yes, 2016
Summary The AWIN applications are specifically designed to allow the on-farm data collection and to provide an immediate and clear visual output on the welfare status of each assessed farm.
C. Dwyer   +12 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Coda vocalizations recorded in breeding areas are almost entirely produced by mature female sperm whales (Physeter macrocephalus) [PDF]

open access: yes, 2008
We investigated the use and function of coda communication by sperm whales (Physeter macrocephalus L., 1758 (=Physeter Catodon L., 1758)) Codas are stereotyped patterns of clicks often made by sperm whales in social contexts. We used the pulsed structure
Marcoux, M, Whitehead, H, Rendell, L
core  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Genetic and phenotypic characterization of intestinal spirochetes colonizing chickens and allocation of known pathogenic isolates to three distinct genetic groups

open access: yes, 1997
Infection with intestinal spirochetes has recently been recognized as a cause of lost production in the poultry industry. Little is known about these organisms, so a collection of 56 isolates originating from chickens in commercial flocks in Australia ...
Oxberry, S.L.   +4 more
core  

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