This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Association between plant and animal protein and biological aging: findings from the UK Biobank. [PDF]
Xu X +9 more
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
'A Necessary Idea Given Our Current Climate': A Qualitative Study of Stakeholder Perspectives and Actions Required to Increase the Proportion of Plant to Animal Protein in Hospital Patient Menus. [PDF]
Stiles G, Collins J, Beck K.
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Association of total, plant, and animal protein intake with hypertension among type 2 diabetic patients in Azar cohort population: A cross-sectional study. [PDF]
Kiani S +3 more
europepmc +1 more source
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Does partial replacement of animal protein with plant protein in the diet affect components of metabolic syndrome, adropin levels, and the atherogenic index of plasma? Results from a parallel randomized clinical trial in adults with metabolic syndrome. [PDF]
Shahdadian F +7 more
europepmc +1 more source
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
The association between animal protein, plant protein, and their substitution with bladder cancer risk: a pooled analysis of 10 cohort studies. [PDF]
Beigrezaei S +16 more
europepmc +1 more source

