Advanced Science, EarlyView.A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li +15 more
wiley +1 more source
Why genetic validation is crucial for identifying larval stages of <i>Arctica islandica</i> (Venerida, Arcticidae). [PDF]
ZookeysChaibi CA, Kniesz K, Zettler ML.
europepmc +1 more source
Advanced Science, EarlyView.Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu +11 more
wiley +1 more source
Winged animal sculpture with pyramid sculpture in the background
Animal sculpture in the Emeryville Mudflats, August ...
Sommer, Robert
core +1 more source
Synopsis of Ant Genus <i>Proceratium</i> Roger, 1863 from China (Hymenoptera, Formicidae), with Description of Seven New Species. [PDF]
InsectsGu Z, Zhang C, Chen Z.
europepmc +1 more source
Real‐Time Ferroelectric Domain Wall Dynamics During Electric Poling and Depoling
Advanced Science, EarlyView.Real‐time visualization of domain wall dynamics during alternating‐current poling, direct‐current poling, and electrical depoling in relaxor‐PT ferroelectric single crystals reveals distinct field‐dependent pathways and strong path dependence. Instant polarized light microscopy uncovers reversible domain wall nucleation, motion, and reconfiguration ...
Ziqi Wang +12 more
wiley +1 more source
Uniqueness and predictability in evolution and the history of mollusks. [PDF]
Proc Natl Acad Sci U S AVermeij GJ, Thomson TJ.
europepmc +1 more source
Structural Colors from Modulated Topological Defects in Molecular Smectic Liquid Crystals
Advanced Science, EarlyView.Rather than using dyes and pigments, nature produces the colors of some butterflies and beetles through optical interference phenomena. This study describes an original biomimetic strategy exploiting the spontaneous formation of modulated linear defects in thin films of 8CB, a common molecular liquid crystal.
Camille N. Mahyaoui +7 more
wiley +1 more source
Examples of wild animals on the Assyrian sculptures - selected samples
Athar Alrafedain, 2012 openaire +1 more source
Impact of landscape installation design on emotional loneliness: interaction style as a moderating factor. [PDF]
Front PsycholGong M.
europepmc +1 more source